Results for technologies (153)
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AI-Powered Deep Phenotyping for Precision Drug Development (No. T4-2443)
Understanding disease biology at the subcellular level is key to precision medicine.
High-content phenotypic screening of therapeutic compounds
Mechanistic insights into drug-induced subcellular effects
Discovery of disease-specific organellar biomarkers
Detects subtle,...
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19425
Cyclic Capture of Atmospheric CO2 (No. T4-2433)
Reducing greenhouse gas emissions alone will not be enough to limit the impacts of climate change - active removal of CO₂ from the atmosphere is essential. CycCap addresses this need with a cyclic process in which a salt solution is electrochemically split into alkaline and acidic streams....
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19247
RF Resonators for Strong Driving of Nuclear Spins (No. T4-2431)
An RF resonator designed for strong and fast driving of nuclear spins with applications in quantum sensing and microscopy. The resonator is a spiral structure composed of two metallic layers separated by an insulating material.
Integration in quantum sensing toolboxes for addressi...
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19127
Dynamic VR-Based Motion Bio-Feedback Algorithm for Active CLP Exposure (No. T4-2420)
Current exposure-based therapies for PTSD, phobias, and ADHD lack personalization, real-time safety monitoring, and patient agency.
Treating ADHD with biofeedback during gamified training sessions
Treating PTSD with AI-assisted triggering environments that recreate the specific tr...
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19198
Synthetic Antimicrobial Peptides for Selective and Potent Malaria Treatment (No. T4-2408)
Malaria remains a major global health challenge, with increasing resistance to current drugs and limited treatment options that selectively target infected red blood cells.
Applications
Selectively targets infected red blood cells while sparing naïve RBCs
Minimal hemol...
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19146
Computationally Designed Peroxygenases for Selective Terpene Oxyfunctionalization (No. T4-2403)
Terpenes represent the largest class of secondary plant metabolites. Their oxyfunctionalized derivatives, terpenoids, are widely used in the pharmaceutical, flavor, and fragrance industries due to their aromatic properties.
Applications
High diversity: All 50 designed e...
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19149
mAb mouse anti-Amphiregulin clone AR37 (No. M7-2388)
The AR37 monoclonal antibody recognizes human and mouse amphiregulin (AREG), a member of the epidermal growth factor (EGF) family.
in vivo blocking of amphiregulin (AREG)in vitro blocking of amphiregulin (AREG)
Immunofluorescence
Western blot
ELISA
Lindzen et al, Oncog...
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19341
AI Based Decision Support System for Age related Macular Degeneration (AMD) and Diabetic Retinopathy (DR) (No. T4-2387)
Diabetic macular edema (DME) and age-related macular degeneration (AMD) are the leading causes of blindness among working-age and elderly populations.
Clinical decision support - automated analysis of OCT volumes and EMRs to suggest next treatment steps.
Precision ophthalmology ...
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19415
Proteasome-Derived Defense Peptides (PDDPs) for Antimicrobial Therapy and Applications (No. T4-2372)
Proteasome-derived defense peptides (PDDPs) represent a novel class of antimicrobial peptides (AMPs) generated through proteasomal degradation. These peptides disrupt bacterial membranes and provide a cell-autonomous defense mechanism against infections.
Sepsis treatment – PDDPs...
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19213
Modulo-Based High Dynamic Range ADC (No. T4-2371)
A novel analog-to-digital conversion pre-processor uses a modulo-based signal folding method to overcome the limited dynamic range of conventional ADCs. The folded signal is reconstructed using a dedicated unfolding algorithm, enabling precise signal recovery across a wide amplitude spectrum...
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19237
High-Resolution Microbial Profiling Across Unexplored Niches Using CoSMIC (No. T4-2368)
Microbial profiling methods based on 16S rRNA sequencing are limited by primer bias, short-read coverage, and databases dominated by human-associated microbes. These limitations reduce phylogenetic resolution and hinder accurate species detection in underexplored environments.
Mic...
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19210
Electrically tunable thin films for smart optical and chiral devices (No. T4-2362)
Modern optics and photonic devices require materials that can actively control both color and light polarization, a combination not currently available in scalable, energy-efficient formats.
Smart windows and adaptive eyewear
Chiral optical switches and light modulators
Polarizati...
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19531
Optical Switches Based on Magnetic Metal-Organic Frameworks (No. T4-2361)
This technology introduces porous, anisotropic metal–organic frameworks (MOFs) with magnetic nanoparticles attached on the surface, enabling precise spatial orientation using external magnetic fields.
Optical and magnetic field sensors
Anti-counterfeiting and document authentica...
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19529
Colloidal Synthesis of Micron-Scale Organic Crystalline Spherulites (No. T4-2334)
A controllable method for synthesizing organic, crystalline spherulites from compounds with guanine-based structures.
Paints and coatings
Food coloring
Cosmetics
Plastics
Ink and tattoo pigments
Supplements
Medicine
Toothpaste
Non-toxic
Biocompatible
Can be applied to ...
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19076
Superconducting Quantum Memory with Tens of Milliseconds Coherence Time (No. T4-2333)
Quantum computing platforms based on superconducting qubits suffer from high error rates and short storage time of only a few milliseconds, limiting scalable computations.
Quantum memory modules in superconducting quantum computers based on Transmon, SNAIL, or Fluxonium qubits.
Pr...
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19339
Compact Very High Energy Electron (VHEE) Radiotherapy for Deep-Seated Tumors (No. T4-2332)
Conventional radiotherapy, including photon-based (X-ray) and proton therapy, often damages surrounding healthy tissue, causing side effects and limiting the dose. These approaches also involve trade-offs in precision, cost, and infrastructure demands.
Advanced, high-precision rad...
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19445
Polymerization-Inducing Chimeras (PINCH) for Selective Target Inactivation (No. T4-2323)
A novel modality for selectively inactivating homomeric proteins, common in disease-driving pathways, by inducing their polymerization.
Functional inactivation of disease-driving homomeric proteins (e.g., transcription factors, metabolic enzymes, scaffold-like proteins etc.)
Poten...
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19253
Flexible Soft-Printed Synthetic and Bio-Polymer Films with Gold Nanoparticles (No. T4-2318)
A novel soft-printing method enables the precise deposition of gold nano-islands (AuNIs) onto flexible synthetic and bio-polymer films.
Cosmetic applications - illuminating masks, under-eye brighteners, blemish covers, and smart patches that visually signal treatment time or expos...
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19243
Smart Energy Storage Devices with Visual Charge Monitoring (No. T4-2316)
The growing demand for energy devices that store and deliver power and offer additional functionalities, like instant performance monitoring, is evident.
Smart batteries and supercapacitors with built-in charge indicators
Wearable electronics with integrated energy storage
Optoele...
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18931
Automated, Accurate Material Detection in Hyperspectral Data (No. T4-2281)
This technology introduces an automated algorithm that detects materials in hyperspectral data with high accuracy and reliability.
Mineral exploration – automated identification of mineral deposits on Earth or other planets
Environmental monitoring – detection of pollution sig...
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19431
Aerobic Electrochemical Oxidation of Hydrocarbons (No. T4-2279)
Aerobic oxidation is a key industrial process for producing valuable chemicals from alkenes and alkanes, abundant in petroleum and natural gas. However, existing methods are inefficient and unsustainable.
Oxidation of ethane to Ethanol and /or Acetic Acid
Electrocatalytic aerobic ...
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18592
Stirring-Free Scalable Electrosynthesis Enabled by Alternating Current (No. T4-2268)
A scalable, stirring-free electrosynthesis method utilizes alternating current (AC) electrolysis to enable efficient redox-neutral, oxidative, and reductive transformations.
Industrial-scale synthesis of chemicals and pharmaceutical ingredients
Synthesis of viscous solutions or re...
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18649
Pmel-1 TCR transduced cells (No. M7-2265)
This T-cell line, derived from the BWZ.36/CD8a thymoma of murine origin, was genetically engineered to express CD3 and a codon-optimized Pmel-1 T-cell receptor (TCR) through sequential retroviral transductions.
Bassan et al., Int J Cancer, 2019.
...
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19345
Time-Encoding Sub-Nyquist ADC (No. T4-2258)
Modern ADCs must reduce cost and power consumption without compromising signal quality, particularly in power-sensitive systems such as wearables, IoT, and security devices. This technology introduces the first sub-Nyquist ADC based on an integrate-and-fire time encoding machine (IF-TEM).
...
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19235
Sparsity Based Non-Contact Vital Signs Monitoring of Multiple People Via Radar (No. T4-2257)
Current contact-based monitoring devices cause patient discomfort, increase infection risks, and demand significant medical staff time.
Medical Monitoring: Heart rate, respiration, sleep apnea detection, lung function, cardiac diagnostics in hospitals, clinics, and homes.
Workplac...
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18610
Task-Specific MIMO Communication Systems (No. T4-2255)
This task-specific MIMO system enables highly accurate signal recovery with minimal hardware complexity and power consumption. It combines task-specific beamforming, low-bit ADCs, and quantized analog combiners to efficiently leverage signal sparsity and suppress spatial interference.
...
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19423
Nonlinear Waveform Inversion for Quantitative Ultrasound (No. T4-2254)
A Nonlinear Waveform Inversion (NWI) algorithm enhances ultrasound imaging by using Recurrent Neural Networks (RNNs) to reconstruct material properties from acquired signals.
Discerning between benign and malignant breast tumors
Identifying muscle loss and fatty muscular degenerat...
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18751
Cell line mutant in the R2-box region of the R2 gene (No. M7-2251)
A CRISPR-Cas9–engineered cell line carrying a mutation in the R2-box region of the R2 gene (within the ERE-homologous 5′UTR) exhibits markedly reduced R2 transcript and protein levels.
...
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19271
GBA mice: a novel Gaucher disease (GD) model (No. M7-2249)
The GBA (Gba⁻/⁻;Gbatg) mouse model represents a chronic neuronopathic Gaucher disease (type 3) model that bridges the gap between acute (type 2) and systemic (type 1) forms.
...
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19369
Nephrostomy Tube – A New Design to Decrease Dislodgement (No. T4-2230)
The existing nephrostomy tube design, widely used for kidney drainage, presents challenges related to accidental premature extraction, necessitating resource-intensive replacement.
Nephrostomy tubes are vital in managing short- and long-term medical conditions, including ureteral ...
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Yaniv Shilo
18868
Anti importin beta1 monoclonal antibody (No. M7-2223)
A highly specific and sensitive anti-Importin b1 (KPNB1) monoclonal antibody. The mAb recognizes an epitope comprising residues 301-320 of human KPBN1 and is highly specific for cytoplasmic KPNB1 in diverse applications.
Importin b1 (KPNB1) is a nucleocytoplasmic transport factor...
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17648
Treating Malaria using Translation Initiation Inhibitors (No. T4-2220)
Malaria, caused by Plasmodium falciparum, remains a leading global health burden with growing drug resistance threatening current therapies.
Malaria, caused by Plasmodium falciparum, remains a leading global health burden with growing drug resistance threatening current therapies....
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19363
An Improved Single-Cell RNA-Sequencing Method (No. T4-2217)
Single-cell RNA sequencing (scRNA-seq) methods enable the detection of only 10%-15% of the cellular transcriptome, rendering low-expressing genes in the dark.
Applications
WRAP-seq is fully developed
TRAP-seq has a POC of several target genes, and is in validation stage...
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18646
Hyperstable Serum Albumin Variants for Microbial Mass Production (No. T4-2216)
Serum albumins are widely used in medicine, biotechnology, and cultivated meat production. However, they are mostly extracted from animal sources, raising ethical, reproducibility, and scalability concerns.
Applications
Fast and economical
Large-scale production in E. c...
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18682
Radiation Curing Enhancement by Semiconducting Nanoparticles (No. T4-2215)
UV curing of polymers plays a critical role in technologies such as dentistry, advanced manufacturing (e.g., 3D printing), optical media production, and biotechnology.
Reinforcement of radiation curing of acrylates
Cation-induced polymerization of epoxies for adhesives
Matrices fo...
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17678
Novel Molecules to Activate Immune Pathways (No. T4-2212)
Bacterial and plant immune systems rely on Toll/Interleukin-1 receptor (TIR) domains to detect pathogens and initiate defense responses through immune signals comprising isomers of cyclic ADP-ribose.
Phage therapy: Engineering “super-phages” expressing Tad1 genes to overcome b...
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19371
Active Macrolide Antibiotic Compounds Against Pathogens (No. T4-2210)
The growing threat of multidrug-resistant bacteria, such as S. aureus and E. coli, underscores the urgent need for next-generation antibiotics.
Treatment of infections caused by drug-resistant Staphylococcus aureus and Escherichia coli
Development of new antibiotics for resistant ...
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18673
GFP variants (No. M7-2209)
A collection of GFP variants with improved/unique properties, such as increased thermostability, photostability, quantum yield, altered fluorescence lifetime, pH sensitivity, and excitation spectra.
The team led by Prof. Fleishman developed a machine-learning-based approach calle...
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18032
OM-17 cell line (high grade serous ovarian carcinoma) (No. M7-2202)
A cell line originated from a patient diagnosed with high-grade serous ovarian carcinoma (HGSOC).
...
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18314
Enhancing Biofuel Production through Engineered Versatile Peroxidases (No. T4-2197)
The growing need for sustainable biofuel alternatives is challenged by the difficulty of breaking down lignin, a major component of plant biomass.
Applications
High expression yields in yeast
Enhanced enzyme stability under industrial conditions
Broad substrate specific...
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18667
Super Resolution Vascular Ultrasound Imaging for Clinical Diagnostics (No. T4-2194)
An advanced deep-learning method for analyzing super-resolution Ultrasound Localization Microscopy (ULM) data to quickly and accurately reconstruct microvasculature structures, without needing prior knowledge of the system's characteristics.
Microvascular imaging using super-resol...
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16721
Parallax depth contrast for scanning probe transmission microscopy (No. T4-2193)
Standard light microscopy generates flat, two-dimensional images of transparent specimens, making it difficult to resolve the spatial arrangement of internal structures. Existing methods to infer depth rely on multiple recordings or complex hardware adjustments, often resulting in inaccuraci...
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19397
Splicing ViT Features for Semantic Appearance Transfer (No. T4-2192)
An AI algorithm using a pre-trained Vision Transformer (ViT) to transfer one image’s appearance onto another’s structure, creating realistic chimeric images automatically and efficiently without extra input.
A feature for AI systems that can create realistic images with di...
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18637
Ab289 (No. M7-2188)
The Anti-JUNV GP1 monoclonal antibody specifically recognizes the receptor-binding domain (GP1) of the Junín virus glycoprotein complex (GPC).
Borenstein-Katz A, Shulman A, Hamawi H, Leitner O, Diskin R. Differential Antibody-Based Immune Response against Isolated GP1 Receptor-Bi...
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Aliza Borenstein Katz
Chemistry
19335
Zirconium Doped Ceria Electroceramic with a High Electrostriction Coefficient (No. T4-2180)
Electrostrictive actuators are devices that convert electrical signals into tiny, precise movements, widely used in medical devices, robotics, and microelectronics.
Medical micro-devices: e.g., miniature insulin pumps and drug-delivery systems.
MEMS and NEMS actuation: micro-posit...
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18925
B16F10.9 Cell Line (No. M7-2179)
Spontaneous metastatic spread of melanoma after surgery of the primary tumor. immunization against melanoma metastasis
Relevance: A model to study melanoma metastasis in mice.
Melanoma metastatic spread, immunization against melanoma metastasis
Relevant disease: melanoma
Porgador ...
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19329
Bispecific Immune Synapse Engagers as Immunotherapy for Oncology and Autoimmunity (No. T4-2176)
Dysfunctional immune circuits underlie many diseases, including cancer and autoimmunity. Current immunotherapies often target a single pathway or cell type, limiting their efficacy.
Treatment of anti-PD-1 refractory solid tumors, including breast, colorectal, lung, and melanoma ca...
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19180
Scalable method for braiding majorana modes in topological superconductor (No. T4-2172)
Quantum computing requires reliable control and braiding of Majorana zero modes. These modes emerge in topological superconductors and enable exceptionally stable quantum operations but are highly sensitive to noise and geometric imperfections.
Quantum computing and simulation.
Er...
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19389
IPHOMED: A Functional Multi-Omics Platform for Decoding Host-Microbiome-Diet Interactions (No. T4-2160)
Understanding the complex interplay between the human host, gut microbiome, and diet is critical for diagnosing and treating diseases like IBD, celiac disease, and metabolic disorders.
Functional profiling of the microbiome in health and disease
Protein biomarker discovery for dia...
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19383
Novel Antibody Therapeutics Targeting Senescent Cells for Cancer and Fibrotic Disease Treatment (No. T4-2158)
Senescent cells play a dual role in cancer and fibrosis, where their persistent presence can drive chronic inflammation, tissue remodeling, and disease progression.
Development as ADCs, BiTEs, or bispecifics for targeted senescent cell elimination
Anti-cancer therapy targeting res...
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19186
MMP14 targeting natural antibodies to treat ovarian cancer (No. T4-2152)
MMP14 is a major antibody target on the tumor cell surface as it is highly expressed on tumor cells and plays a key role in cancer progression and metastasis. Natural occurring autoantibodies targeting MMP14 were isolated from ovarian cancer patients.
Monoclonal antibody therapy...
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17825
Novel Combination Therapy For Improved Management of Depression (No. T4-2129)
A novel combination therapy pairing ketamine with retigabine, an FDA-approved KCNQ channel activator, offers a promising strategy for mood-related disorders.
Potential to expand treatment opportunities for patients with treatment-resistant depression (TRD) unresponsive to existing...
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6097
Reusable Gold Nanostars Substrates for Signal Amplification for Diagnostics (No. T4-2127)
Numerous spectroscopic techniques rely on signal enhancement from nanoparticles linked to analyte molecules. However, existing surface-enhanced spectroscopies (SES) typically use nanoparticles dispersed in solution, making them unsuitable for solid substrates.
Signal amplification...
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12950
Biofilm-Targeting Liposomes for Enhanced Antimicrobial Delivery (No. T4-2115)
Microbial biofilms limit antibiotic penetration and can require substantially higher drug exposure than free-floating bacteria.
Treatment of Pseudomonas aeruginosa biofilm infections
Antimicrobial delivery for chronic and infected wounds
Treatment of biofilm-associated medical dev...
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Monika Kluzek
Chemistry
19568
Modified Gabor Representation: A Powerful New Method forClassification and Compression of Audio, Images and Signals (No. T4-2100)
The Periodic Gabor with Biorthogonal Exchange (PGB) method is a cutting-edge technology for compressing and classifying audio, images, and signals.
Audio: Compresses audio with high fidelity and low computational load; outperforms STFT in classifying FSDKaggle2018, musical instrum...
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19373
A Method for Vitamin D Production (No. T4-2086)
A sustainable method to produce vegan Vitamin D using the microalga Emiliania huxleyi. This approach enables efficient production of both Vitamin D2 and Vitamin D3, along with additional nutritional values, in a dry biomass form suitable for nutritional supplements.
Nutritional Su...
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18442
Modulating Weight Gain and Loss by Understanding the Mechanism of Smoking Related Weight Changes (No. T4-2078)
A new approach to prevent weight gain during smoking cessation (SCWG) focuses on the gut microbiome and metabolites like dimethylglycine (DMG) and acetylglycine (ACG).
Modalities for Weight Management: Development of treatments targeting these metabolites to aid in weight loss.
...
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17357
Biosynthetic pathways for producing Psychedelics (No. T4-2077)
Applying a multitude of enzymes to generate biosynthetic pathways to synthesize different Psychedelics such as DMT, Psilocin, Psilocybin, Peyote related compounds, and so on.
Production of a series of different Psychedelic compounds
Potential to modify the compounds by including ...
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19433
Enhanced Anti-PD-L1 Immunotherapy (No. T4-2059)
A novel approach for enhancing the efficacy of PD-L1 targeting antibodies by harnessing beneficial FcγR signaling pathways.
Strategy involves either
(1) Co-administration of PD-L1 targeting antibodies with an FcγRIIB-blocking antibody or
Enhanced anti-PD-L1 therapy for cancer tr...
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17039
APP–Tau bispecific peptide inhibitor for the treatment of Alzheimer’s Disease (No. T4-2057)
The interaction between APP and Tau, two central drivers of Alzheimer’s pathology, is increasingly recognized as a critical factor in disease progression.
Disease-modifying treatment for Alzheimer's disease
Preventive therapy for individuals at risk of developing AD
Potential us...
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Ruth Arnon
Faculty of Biology
6160
Three Phases Topological Superconductivity (No. T4-2055)
Realizing topological superconductivity and stable Majorana zero modes, which are envisioned for use in topological quantum computers, typically requires large magnetic fields (around .1 T). However, these strong magnetic fields can suppress superconductivity and hinder device integration. ...
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19379
Spin Current and Magnetoresistance from the Orbital Hall Effect (No. T4-2053)
An innovative method to generate spin current and magnetoresistance by leveraging the Orbital Hall Effect (OHE). This approach utilizes ordinary metals like Aluminum and Copper, combined with a thin layer of heavy metal to convert orbital currents into spin currents.
Magnetic fiel...
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18700
YotiCurl Ureteral Stent (No. T4-2052)
Kidney stones affect millions worldwide, with up to 15% of the population experiencing them during their lifetime. Obstructing stones often require insertion of a temporary ureteral stent to maintain urine flow.
Relief of ureteral obstruction caused by kidney stones
Pre- and post-...
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18871
Coupling of Alternating Current to Transition – Metal Catalysis (No. T4-2050)
A method for coupling alternating current (AC) electrolysis to transition-metal catalysis, enabling enhanced catalytic reactions with higher yields and selectivity.
Catalytic systems where one or several steps can be accelerated by electrochemical oxidation/reduction
Transition...
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18308
Covalent Chemistry Platform for Diagnostics and Drug Discovery (No. T4-2045)
CoLDR (Covalent Ligand-Directed Release) chemistry enables site-specific covalent labeling and activation of endogenous proteins using small-molecule covalent ligands.
Targeted prodrug activation in cancer and inflammatory diseases
Drug and probe delivery with selective activation...
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6106
Protein coupling using cystein-free inteins (No. T4-2039)
Traceless covalent modification of proteins, including joining peptides or adding chemical groups, is extremely useful for numerous applications in chemical biology, protein chemistry, and biotechnology.
Modifying or joining proteins with other proteins/ peptides/chemical groups i...
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6862
Circulating microRNA Biomarkers for Early Frontotemporal Dementia Diagnosis (No. T4-2037)
Frontotemporal dementia (FTD) is difficult to diagnose due to overlapping symptoms with other neurodegenerative disorders, often leading to delays in treatment and clinical trial enrollment.
Early and accurate FTD diagnosis – Reduces misdiagnosis and diagnostic delays
Clinical t...
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6082
Scarless CRISPR-mediated Genome Editing (No. T4-2036)
CRISPR-Cas9 is a widely-used tool for genome editing; however, it is very inefficient and often requires the addition of selection markers, forcing the introduction of foreign DNA elements.
CRISPR-Cas9 method, while promising, is currently inherently inefficient and requires selec...
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6112
Safer CAR-T Cell Platform (No. T4-2033)
A platform for engineering CAR-T cells with enhanced cancer-killing ability and reduced toxicity. By redesigning the transmembrane domain of the CAR using a computational protein design platform, researchers created synthetic receptors that form stable, specific oligomeric structures.
...
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6124
AI-Driven Discovery Platform for Immune Protein Inhibitors (No. T4-2027)
There is a growing need for innovative strategies to selectively target key drivers of immune-mediated diseases.
Discovery of highly specific protein inhibitors targeting key human immune molecules, enabling the development of novel biologics for autoimmune and inflammatory diseas...
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19381
Carbon Nanotubes - Polymer Composites for Improved Mechanical and Electrical Properties (No. T4-1953)
The superior mechanical and electrical properties of carbon nanotubes (CNTs) are uniquely advantageous for enhancing polymer composites' mechanical and electrical properties. However, CNTs usually heavily bundle.
Markets continuously search for stronger, more durable, lightweight,...
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18922
Small Molecules for Treatment of Huntington's Disease and Related Disorders (No. T4-1947)
A new class of small molecules offers a targeted strategy for treating Huntington’s disease (HD) and related trinucleotide repeat expansion disorders (TREDs).
Treatment of Huntington’s Disease (HD)
Potential treatment of other TREDs, including: Spinocerebellar Ataxias 1, 2, 3 ...
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6193
Microbiome Therapeutic for Treating Bacterial Vaginosis (No. T4-1945)
Bacterial vaginosis (BV) frequently recurs after antibiotic treatment, leaving patients with limited options for durable disease control.
Treatment of recurrent or antibiotic-refractory bacterial vaginosis
Microbiome-based donor selection and treatment monitoring
Hi...
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6088
New Antiviral Drugs from Bacterial Natural Products (No. T4-1934)
There is a growing need for effective antiviral therapies, particularly for viruses that currently lack approved treatments.
Treatment of viral infections with no currently approved antiviral therapies
Development of broad-spectrum antiviral drugs
Nucleotide chain term...
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12514
Higher Efficiency of CRISPR Gene Editing Using Chimeric Cas9 (No. T4-1930)
CRISPR-Cas9 is a powerful tool for genome editing, widely used for basic research and the development of treatments for genetic diseases. However, its efficiency is currently limited.
Gene therapy applications
Basic science research
Simple implementation – requires o...
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6024
Novel TCRs against mutated KRAS, NRAS, and androgen receptor, and neoantigens identification platform (No. T4-1926)
Immunotherapy can induce durable tumor regression in patients with metastatic cancer, largely driven by the immune system’s recognition of tumor-specific neoantigens.
Discovery and validation of TCRs against common immunogenic neoantigens
Off-the-shelf TCR cell therapy for cance...
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19192
Anti-LOX for the Treatment of Duchenne, Fibrosis and Cancer (No. T4-1913)
LOX is a key driver of fibrosis and tumor progression through its role in extracellular matrix remodeling. We developed a set of LOX inhibitors based on LOX’s natural prodomain (LPD) to treat fibrosis, Duchenne Muscular Dystrophy (DMD), and cancer.
Treatment of fibrotic disease...
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6026
Continuous Biooptical Monitoring of Microalgae Crops (No. T4-1908)
Microalgae hold immense potential as sustainable sources of food, feed, and biofuels. However, growers often face frequent and unpredictable crop collapses caused by biotic and abiotic stresses.
Monitoring of microalgae farming
Aquaculture monitoring (fish, macroalgae, mollusks)
W...
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14678
Iron Catalyzed Ring-Opening Metathesis Polymerization (ROMP) (No. T4-1905)
A novel iron-catalyzed Ring-Opening Metathesis Polymerization (ROMP) of olefins, which leads to several new catalytic reactions and enables the synthesis of new polymeric materials.
New polymeric materials (i.e. Polydicyclopentadiene, Polyoxanorbornene and Cyclooctene-based polyme...
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6199
GreenTap - A Method for Stimulating Production and Extraction of Metabolites in Plants (No. T4-1894)
A method for inducing and extracting valuable plant metabolites without damaging the plant or interfereing with compound formation.
Production of Bioactive Compounds: Increases yield of plant metabolites used in pharmaceuticals, food, and cosmetics.
Novel Metabolite Discovery: Pro...
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6029
A Sustainable Process for Phenol Production (No. T4-1892)
A sustainable method for phenol production using electrocatalytic oxidation of benzene.
Production of phenol from benzene
Production of acetaldehyde from ethylene
Production of malonic and/or pyruvic acids from acrylic acid
Production of various alcohols from aliphatic and arom...
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5728
Universal CAR-Ts for Treating Cancer (No. T4-1884)
Autologous CAR-T therapies face significant manufacturing complexity and cost, while their efficacy against solid tumors remains limited.
Off-the-shelf allogeneic CAR-T therapies for hematological malignancies
Allogeneic CAR-T therapies for solid tumors
Enhanced effica...
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Zelig Eshhar
Biology
5722
Optical Bus for a Multi-Core Processor (No. T4-1863)
A compact on-chip optical layer that replaces traditional wiring in multi-core processors using silicon photonics. This innovative approach significantly reduces power consumption, heat generation, and space requirements, enabling higher core densities and improved inter-core communication.
...
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5704
Super-Resolution Using Unsupervised Deep Internal Network (No. T4-1850)
Most super-resolution and image enhancement methods rely on large, paired training datasets and predefined distortion models, limiting their effectiveness on real-world images acquired under unknown, variable, or suboptimal conditions.
Enhances low-resolution images acquired under...
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5701
Composite Functional Metasurfaces for Multispectral Achromatic Optics (No. T4-1845)
A new technology for producing flat optical components based on optical metasurfaces. These components can potentially serve high resolution imaging, spectrometry, light processing and beam shaping devices.
The proposed technology can be used to generate a wide variety of novel ...
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5689
Secure Search of Encrypted Cloud Data (No. T4-1840)
Searchable symmetric encryption with practical big-data performance and strong security
Highlights
...
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5683
MAPP - A Method to Identify Actively Degraded Proteins (No. T4-1832)
MAPP (Mass Spectrometry Analysis of Proteolytic Peptides) is a groundbreaking technology that isolates and identifies proteins actively degraded by the proteasome, offering an unparalleled and direct view of the "active degradome." This innovative approach provides a sensitive an
...
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6030
Inertial NEMS for Nanosensor Applications Based on Inorganic Nanotubes (No. T4-1828)
Inertial sensors for motion detection are increasingly integrated into portable devices, including IoT applications, mobile phones, wearables, automotive systems, and medical diagnostics. The demand for smaller electronics is driving innovation in miniaturized components.
IoT devi...
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5674
Synthetic Immune Niche for Enhanced T Cell Expansion and Function (No. T4-1810)
Efficient generation of large quantities of functional T cells is a major bottleneck in the development of T cell-based immunotherapies. Conventional ex-vivo culturing methods often lead to cell death or functional loss.
Expansion of CD4+ and CD8+ T cells for cancer immunotherapy
...
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Nir Friedman
Biology
5665
Microbiome-Based Prediction, Diagnosis, and Treatment of Relapsing Obesity (No. T4-1805)
A novel gut microbiome-based method has been developed to predict and prevent weight regain after weight loss.
Predictive Diagnostic Tool: Provides a microbiome-based test to identify individuals at high risk of post-diet weight regain.
Personalized Approach: Uses a mac...
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5659
Structure-Guided Antibiotic Discovery Platform for MRSA (No. T4-1760)
Antibiotic-resistant bacteria such as Staphylococcus aureus (MRSA) are a growing threat, causing severe infections that are increasingly untreatable by existing drugs. This technology provides a high-resolution crystal structure of the large ribosomal subunit (50S) from pathogenic S.
...
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19255
Treating Cancer and Collagen-Associated Diseases by Using Anti-LOXL-2 Antibody (No. T4-1743)
An innovative method for treating diseases associated with dysregulation of collagen fibers in the extracellular matrix (ECM), such as cancer and fibrosis, by targeting LOXL-2.
ECM disruption is associated with many pathological conditions, such as various cancer types and tissue...
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5611
Carbon Fixing Bacteria (No. T4-1736)
A bacteria (E. coli) engineered to fix atmospheric CO₂, converting it into organic biomass.
Potential Precision Fermentation Platform: A modular platform for producing various chemicals with net negative CO₂ emissions by integrating synthetic metabolic pathways.
Sus...
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5608
Green Chemistry for Ketones and Aldehydes Production (No. T4-1722)
A novel green chemistry approach for producing ketones and aldehydes through an oxidative cleavage reaction. The process utilizes polyoxometalate (POM) catalysts to achieve aerobic cleavage of carbon-carbon double bonds in alkene.
Industrial organic chemistry processes for oxid...
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5596
Metal Organic Frameworks (MOF) for Gas Adsorption (No. T4-1684)
High-performance materials for gas storage and separation are essential for industrial, environmental, and energy-related applications. Conventional MOFs offer molecular-level control but lack tunability at the micro- and nanoscale.
Gas storage and transportation (e.g., hydrogen, ...
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19533
Magnetic resonance imaging (MRI) Of Tissue Fibrosis without Contrast Agent (No. T4-1665)
Cardiac fibrosis, a scarring process that impairs cardiac function and increases the risk of sudden death, remains difficult to detect at early stages with current imaging tools.
Early and non-invasive detection of myocardial fibrosis in hypertensive, diabetic, or post-infarction ...
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5575
Optimized MAGE-A1 targeting TCR for T-cell Therapy (No. T4-1662)
TCR gene therapies show promise in cancer treatment but are hindered by the low natural avidity of TCRs against tumor-associated antigens. MAGE-A1 is a germline antigen expressed in many tumor types, making it a compelling target for TCR-based immunotherapy.
Cell therapy for MAGE-...
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5572
Repurposing Enoxacin: A Novel Therapeutic Strategy Targeting miRNA Biogenesis in ALS (No. T4-1632)
A novel therapeutic strategy for Amyotrophic Lateral Sclerosis (ALS) targets impaired microRNA (miRNA) biogenesis—a key molecular defect found in both sporadic and familial ALS.
Treatment of ALS
Repurposes an FDA-approved drug, reducing development time and regulato...
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18887
Targeted Inhibition of ADAM17 for the Treatment of Inflammatory Diseases and Cancer (No. T4-1628)
ADAM17 is a metalloprotease that regulates shedding of membrane-bound proteins, including IL-6, TNF-α, and others. ADAM17 is implicated in inflammatory diseases, fibrosis, cancer, and autoimmune conditions, making it a compelling target.
Treatment of autoimmune, inflammatory and ...
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5551
Novel MRI Contrast Agent (No. T4-1604)
Novel reporter gene for magnetic resonance imaging applications.The ability to image the duration and location of gene expression in vivo and noninvasively is imperative for the future of biology and clinical medicine.
Non-invasive imaging of gene expression in transgenic mice mod...
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5545
A Novel Database to Reduce Unsuccessful Cloning in E. Coli by Detection of Toxic Genes (No. M7-1576)
Synthetic genes are commonly used in academic and industrial applications, however in many cases these said genes can be toxic when inserted into the ubiquitously used E. coli. This is problematic as time and money is wasted on attempts to generate genes that will not function in E. coli.
...
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5530
Green Catalytic Formation of Alcohols, Amines, Amides, Imines and Esters under Mild Conditions (No. T4-1551)
The production of alcohols, amines, amides, imines, and esters is central to pharmaceuticals, polymers, dyes, fragrances, and agrochemicals, but conventional syntheses require harsh conditions, toxic reagents, and expensive noble metals.
Synthesis of amines, alcohols, amides, imin...
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5512
Production of Amines from Alcohol and Ammonia (No. T4-1507)
Current methods for synthesizing primary amines require high energy input, toxic reagents, and result in undesired byproducts. This technology offers a direct, single-step catalytic process using alcohols and ammonia under mild conditions.
Industrial synthesis of primary amines fo...
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5494
Highly Sensitive Nanoscale Scanning Magnetic and Thermal Sensor (No. T4-1481)
A nanoscale Superconducting Quantum Interference Device (SQUID) on Tip (SOT) that enables high spatial, magnetic, and thermal resolution for local imaging.
Scanning Probe Microscope
Cryogenic Thermal Imaging (mK Temperatures)
Metrology Tools for Quantum Circuits
Imaging of Electri...
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5482
Improved Treatment for Glaucoma (No. T4-1433)
Glaucoma is a leading cause of irreversible blindness driven primarily by elevated intraocular pressure (IOP). Existing therapies often have limited efficacy and side effects, and many patients require combination treatments and are non-compliant.
Treatment of glaucoma through red...
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6232
High-Performance Electrochromic Devices (No. T4-1380)
Current electrochromic materials offer a broad color range and moderate electrochromic activity. However, real-world applications demand more intense coloration, faster switching times, and improved stability.
Smart color-changing glass (windows/glasses/mirrors/windshields etc.)
C...
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5458
Cholesterol Antibodies (No. T4-1267)
Description: Monoclonal antibodies specific for cholesterol/ceramide-rich domains (clones 405F, 14F, 499F) and cholesterol micro-domains (clones 36A1, 5881) in cell membranes. Originally raised against an artificial monolayer of lipid mixtures in, and were shown to specifically label the ab...
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5449
DNA Repair-Based Blood Test for Lung Cancer Risk Assessment (No. T4-1033)
Early detection with low-dose CT (LD-CT) reduces lung cancer mortality by 20%, yet eligibility is limited and patient compliance remains low. MyRepair is a mechanism-based blood test designed to identify high-risk individuals for LD-CT screening — independent of smoking history.
...
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5428
Polyclonal anti human MUC2-D3 (No. M7-442)
A rabbit polyclonal antibody that detects D3 domain of Mucin-2. It targets an epitope within D3
domain from the N-terminal half, which is localized in amino acids 858-1259.
Javitt, G., et. al. (2020). Cell.183(3): 717-729).
...
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Tal Ilani
Faculty of Chemistry
19323
Anti - gp100 T - cell Secreting Hybridoma [BUSA14 cell line] (No. M7-397)
Hybridoma cell line [clone BUSA14] which generates lacZ inducible CD8+ T -cells capable of recognizing both human and mouse gp100(25-33) melanoma antigens presented on dendritic and tumor cell lines.
Cafri G, Sharbi-Yunger A, Tzehoval E, Eisenbach L. Production of LacZ Inducible T...
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Adi Sharbi-Yunger
Biology
Gal Cafri
Esther Tzehoval
Faculty of Biology
19317
Cntnap2 Tlacz/Tlacz Mice (No. M7-394)
Jax Strain #:028635
Cntnap2tlacz/tlacz knockin/knockout mice have a tau-LacZ gene and a neo cassette replacing exon 1 of the Cntnap2 gene. These mice may be useful for studying neuronal circuitry involved in some neurological disorders.
Gordon A , et al. Mol Cell Neurosci, 2016
...
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19301
Immortalized Prostate Cell Cultures PF179T-Prostate Fibroblasts h-TERT Immortalized Cells (No. M7-375)
Recent studies have established the notion that fibroblasts are prominent modifiers of cancer progression, with a specific subpopulation designated as cancer-associated fibroblasts (CAFs) that play a key role in promoting tumor initiation and progression.
Madar S, Bro...
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19319
Immortalized Prostate Cell Cultures PM151T-Prostate Muscle Cells h-TERT Immortalized Cells (No. M7-374)
Parental Line: PM151 cells derived from a radical prostatectomy specimen of a 62-year-old patient. Pathologic tumor stage was also pT3a, Gleason score 5 (3 + 2). The specimen had a positive margin, meaning that the tumor extended the prostate capsule. Seminal vesicles were tumor-free.
...
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19343
Immortalized Prostate Cell Cultures EP156T-Epithelial Prostate h-TERT Immortalized Cells (No. M7-373)
EP156 cells were derived from a radical prostatectomy specimen of a 66-year-old patient. Pathologic tumor stage was pT3a, Gleason score 7 (4 + 3). The specimen had a positive margin, meaning that the tumor extended the prostate capsule. Seminal vesicles were tumor-free.
...
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19309
Escherichia coli UTL2 (No. M7-358)
Escherichia coli UTL2 Description: A "leaky" strain of E. coli, which is significantly more susceptible to cytotoxic agents. UTL2 holds a mutation in the galU gene causing an impaired outer membrane.
...
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5425
CNTNAP2 Knock Out Mouse Model for Human Diseases (No. M7-330)
Jax Stock # 017482
Cntnap2 (contactin-associated protein-like 2) knockout mice lack detectable mRNA or protein expression in brain tissue and serve as a robust model for Cortical Dysplasia-Focal Epilepsy Syndrome and autism spectrum disorders (ASD).
Poliak S , et al. 2003, J Cell...
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19273
Anti-Mast cell Function-associated Antigen (MAFA) monoclonal antibody (No. M7-320)
320 - Monoclonal antibody G63 Description: Monoclonal antibodies to MAFA (Mast cell Function-associated Antigen), originally raised against intact rat RBL-2H3 cells.
...
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5422
Anti-Runx-3 monoclonal antibody (No. M7-306)
Monoclonal antibody to Runx-3 Description: Monoclonal antibody to Runx-3 raised against the Runx3 peptide TPSTPSPRGSLSTTSHF. Available clones: 62, H8.
...
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5416
CX3CR1-Cre ER Mice (No. M7-293)
Cx3cr1CreER knock-in/knock-out mice express tamoxifen-inducible Cre recombinase under the direction of the Cx3cr1 promoter in the mononuclear phagocyte system, making them useful for fate-mapping studies of the monocyte and macrophage compartment, as well as microglia.
Yona S , et...
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19265
CX3CR1-Cre Mice (No. M7-292)
Cx3cr1-Cre mice express Cre recombinase under the direction of the Cx3cr1 promoter in the mononuclear phagocyte system, making them useful for fate-mapping studies of the monocyte and macrophage compartments, as well as microglia. These mice do not express endogenous Cx3cr1.
Yona ...
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19263
Anti-Estrone-3-Glucuronide monoclonal antibody (clones: 155B3, 8A3) (No. M7-276)
Monoclonal antibodies raised against estrone-3-glucuronide-BSA. Available clones: 8A3 (Rat, IgG2a), 155B3. Estrone-glucuronide is the dominant metabolite of estradiol. Used as one reference method for determining ovulation.
Monitoring ovarian function by the simultaneous t...
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5413
Anti-Estrone-3-Glucuronide monoclonal antibody (No. M7-275)
Monoclonal antibodies raised against estrone-3-glucuronide-BSA. Available clones: 8A3 (Rat, IgG2a). Estrone-glucuronide is the dominant metabolite of estradiol. Used as one reference method for determining ovulation.
Monitoring ovarian function by the simultaneous time-resolved fl...
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5410
Anti- estrone-3- glucuronide monoclonal antibody (No. M7-273)
Betatypic anti-idiotypic antibody raised against anti- estrone-3- glucuronide (clone 8A3). Available clone: 7C1.
Monitoring ovarian function by the simultaneous time-resolved fluorescence immunoassay of two urinary steroid metabolites.
Barnard G, Kohen F.Clin Chem. 1998 J...
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5404
Monoclonal Anti-Ermin Antibody (Mab#160) (No. M7-258)
258 - Monoclonal antibody to Ermin Description: Monoclonal antibody to Ermin (MAb160) raised against purified GST–Ermin (residues 1–261).
...
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Damian Brockschnieder
5389
Monoclonal Anti-Gliomedin Antibody (Mab#94) (No. M7-257)
257 - Monoclonal antibody to Gliomedin Description: Monoclonal antibody to Gliomedin (MAb 94) raised against a synthetic peptide corresponding to amino acid residues 273–287 (CVIPNDDTLVGRA), present in the extra cellular region of Rat Gliomedin.
...
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5386
mAb anti ERK1/2 (ERK-PT115) (No. M7-177)
176-177 - Monoclonal antibodies to phospho-ERK/Map Kinase
...
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5359
Anti-Phospho-ERK (PY193 or PT115) Monoclonal Antibodies (No. M7-176)
176-177 - Monoclonal antibodies to phospho-ERK/Map Kinase Description: Monoclonal antibodies raised against peptides containing the 11 amino acids, HTGFLTEYVAT, corresponding to the ERK activation loop either Tyr -phosphorylated (ERK-PY193), or Thr-phos
...
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5356
Clone 1E11 Progesterone (No. M7-146)
Anti-progesterone. Monoclonal antibody raised against position 11 of progesterone (Clone 1E11). It is very specific for progesterone.Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
...
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9580
Anti-oestradiol-6-carboxymethyl oxime monoclonal antibody (No. M7-141)
Monoclonal antibodies to estradiol Description: Monoclonal antibodies raised against oestradiol-6-carboxymethyl oxime-BSA. Available clones: 2F9 (Rat, IgG2a), 15 (IgG2b), 8D9 (IgG2a).
Direct chemiluminescence immunoassay for estradiol in serum. De Boever J, Kohen F, Usanachitt C, ...
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5335
Anti-progesterone-7 monoclonal antibody (No. M7-138)
Monoclonal antibodies raised against position 7 of progesterone (clone 2H4), Rat IgG1. Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food produc...
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5332
Human T3N1M1 prostatic adenocarcinoma tissue for xenograft (No. M7-132)
WISH-PC frozen tissue samples
...
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Zelig Eshhar
Biology
5329
Anti-idiotypic antibody against anti-Sulfamethazine (12E12) (No. M7-130)
Betatypic anti-idiotypic antibody raised against anti Sulfamethazine –KLH (clone 21C7). Available clone: 12E12.
Generation of an anti-idiotypic antibody as a surrogate ligand for sulfamethazine in immunoassay procedures/
...
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5326
Anti-testosterone 3-(0- carboxymethyl)oxime-BSA monoclonal antibody (No. M7-119)
Rat monoclonal antibodies raised against testosterone 3-(0- carboxymethyl)oxime-BSA. Available clones: 5F2, 5A4.Testosterone is the principal male sex hormone and an anabolic steroid.
Preparation of monoclonal antibodies able to discriminate between testosterone and 5 alpha-dihydr...
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5317
Anti-Biotin Antibody (No. M7-116)
Monoclonal anti-biotin antibody (clone F1). Very specific for biotin.
Preparation and properties of anti-biotin antibodies.
...
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5308
Anti-Sulfamethazine monoclonal antibody (No. M7-115)
Monoclonal antibody to Sulfamethazine (SMZ) Description: Rat monoclonal antibodies raised against Sulfamethazine-BSA. Available clone: 21C7, IgG1. Sulfamethazine is an antibacterial agents commonly given to food animals (swine, fishetc.) to prevent disease and maximize production.
...
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5305
An endothelial-adipose cell line derived from a murine bone marrow stroma (14F1.1) (No. M7-103)
103 - Bone marrow derived stroma cell line 14F1.1
Description: An endothelial-adipose cell line derived from a murine bone marrow stroma.
...
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5302
Anti-leukotriene antibody - LTC4 (6E7) (No. M7-101)
Rat monoclonal antibodies raised against Leukotriene C4-KLH. Available clone: 6E7 (IgG1). Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.
...
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5299
Innovative Pulsed Magnetic Field Gradient Technique for Enhanced Nanoscale MRI (No. T4-2452)
A switchable magnetic field gradient on a tip designed to significantly enhance nanoscale MRI resolution and sensitivity achieved in modern nanoMRI sensors, which use permanent magnets.
Applications
Simple and robust fabrication
Short measurement time and enhanced effic...
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19163
Baffinity B-probe: Cell-Surface-Biomarkers Detection Platform (No. T4-2487)
Accurate detection of minimal residual disease (MRD) is critical for predicting relapse in hematological cancers. However, current diagnostic tools often fail when therapeutic antibodies mask target markers, leading to false negatives.
Detection of MRD markers in blood samples fro...
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19239
360° Rotating Field Transcranial Magnetic Stimulation (rfTMS) (No. T4-2472)
Transcranial magnetic stimulation (TMS) is an FDA-approved, non-invasive treatment for depression, OCD, and migraines. However, its efficacy is limited by the fixed directional orientation of standard TMS, which only stimulates axons aligned with the field.
Treatment-resistant dep...
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19251
Controlling the Acoustic Spectrum in Fast MRI to Reduce Noise and Imaging Artifacts (No. T4-2470)
Fast MRI sequences such as echo-planar imaging (EPI) generate strong mechanical vibrations in the scanner, producing loud sounds, image ghosting, and possible hardware strain, issues that are amplified at ultra-high magnetic fields.
Low-noise MRI protocols for sensitive patient po...
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19367
AI-Designed Proteins for Bacterial Domestication (No. T4-2489)
Bacterial defense systems often block plasmid delivery, limiting strain engineering and biomanufacturing.
Enabling efficient transformation of previously untransformable bacterial strains
Increasing plasmid delivery and expression efficiency in industrial hosts
Expanding the genet...
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19375
Event-Based Perceiver for Small or Distant Object Detection (No. T4-2471)
The Event-Based Perceiver (EBPer) is an advanced vision system that enables high-resolution detection of small or distant objects with exceptional energy efficiency.
Low-power pest and disease detection in smart agriculture
High-resolution, low-power object tracking for micro and ...
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19385
Non-Contact Fluid Level Detection in Opaque Containers (No. T4-2469)
A novel AI-powered imaging technology that accurately determines fluid levels in opaque containers. It employes a speckle-based vibrational imaging system using a cost-effective camera-laser system and a deep learning-based inference.
Building and infrastructures: Structural monit...
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19393
Bispecific EGFR/MERTK Antibody to Overcome Resistance to Tagrisso in Lung Cancer (No. T4-2493)
Lung cancer patients treated with the blockbuster drug Osimertinib (Tagrisso) eventually develop resistance. We identified a novel MERTK-dependent escape mechanism, that occurs even in the absence of new mutations and is estimated to account for more than 60% of resistance cases.
...
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19475
BioSynthetic pathway for β-carbolines (Plants and Microbial Expression Systems) (No. T4-2538)
β-carbolines are bioactive indole alkaloids best known for their neuroactive properties as monoamine oxidase inhibitors, with established relevance in psychiatric contexts and emerging roles in oncology and inflammation.
Pharmaceuticals: neuroactive compounds acting as monoamine ...
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19481
4-1BB bispecific for improved cancer immunotherapy (No. T4-2475)
We disclose a novel approach to bypass dose-limiting toxicity of 4-1BB agonists, the major limiting factor for the clinical development of 4-1BB mAbs for cancer immunotherapy: mutating 4-1BB ligand to attenuate its potency and fusing it to an antibody targeting defined immune cells which con...
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19483
Random Copolymers for Lubrication Applications (No. T4-2498)
Many hydrogel-based lubricants provide excellent performance on hydrophilic surfaces but lose effectiveness on hydrophobic materials, limiting their use in medical devices and other applications.
Lubricious coatings for urinary catheters, stents, and other implantable medical devi...
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19546
Anti-Klk4 Allosteric Antibody for Cancer Treatment (No. 2276)
Kallikrein-related peptidase 4 (KLK4) plays a significant role in cancer progression and has emerged as a clinically relevant biomarker for ovarian cancer.
Treatment of ovarian cancer
Targets a structurally unique, non-conserved allosteric site, enabling specific targe...
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19548
First-in-Class Immune-Tolerizing Peptide Therapeutics for IBD (No. T4-2536)
Inflammatory bowel disease (IBD) remains a major unmet medical need, with current therapies relying on chronic immunosuppression rather than restoring immune tolerance.
Immune tolerance-inducing therapies for Crohn's disease and ulcerative colitis
Prevention of disease flares thro...
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19552
High-Sensitivity Organic Pyroelectric Quasi-Racemic Crystals with Low Mechanical Noise (No. T4-2497)
Advanced thermal imaging, sensing, and memory devices require pyroelectric materials that combine high sensitivity with low mechanical noise and environmental sustainability.
Pyroelectric sensors and detectors with minimal noise
Thermal cameras, IR detection, thermal imaging
Memor...
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19558
All-Solid-State Electrochromic Device Based on a Multifunctional Ceramic Proton Conductor (No. T4-2496)
Electrochromic devices for smart windows, mirrors, and optical components rely on proton-conducting electrolytes and separate counter-electrode layers—systems that often suffer from poor stability, complex fabrication, and high cost.
Smart windows with dynamic control of light t...
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19560
Turn-On Fluorescent Protein Sensors (No. T4-2462)
Detection of proteins and their isoforms in complex biological environments remains limited by low sensitivity, poor selectivity, and high background signal in conventional fluorescent probes.
Clinical diagnostics: Detection and differentiation of disease-associated protein biomar...
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19562