The AR37 monoclonal antibody recognizes human and mouse amphiregulin (AREG), a member of the epidermal growth factor (EGF) family. ... Read more

This T-cell line, derived from the BWZ.36/CD8a thymoma of murine origin, was genetically engineered to express CD3 and a codon-optimized Pmel-1 T-cell receptor (TCR) through sequential retroviral transductions. ... Read more

A CRISPR-Cas9–engineered cell line carrying a mutation in the R2-box region of the R2 gene (within the ERE-homologous 5′UTR) exhibits markedly reduced R2 transcript and protein levels. ... Read more

The GBA (Gba⁻/⁻;Gbatg) mouse model represents a chronic neuronopathic Gaucher disease (type 3) model that bridges the gap between acute (type 2) and systemic (type 1) forms. ... Read more

A highly specific and sensitive anti-Importin b1 (KPNB1) monoclonal antibody. The mAb recognizes an epitope comprising residues 301-320 of human KPBN1 and is highly specific for cytoplasmic KPNB1 in diverse applications. ... Read more

Single-cell RNA sequencing (scRNA-seq) methods enable the detection of only 10%-15% of the cellular transcriptome, rendering low-expressing genes in the dark. ... Read more

Serum albumins are widely used in medicine, biotechnology, and cultivated meat production. However, they are mostly extracted from animal sources, raising ethical, reproducibility, and scalability concerns. ... Read more

Bacterial and plant immune systems rely on Toll/Interleukin-1 receptor (TIR) domains to detect pathogens and initiate defense responses through immune signals comprising isomers of cyclic ADP-ribose. ... Read more

A collection of GFP variants with improved/unique properties, such as increased thermostability, photostability, quantum yield, altered fluorescence lifetime, pH sensitivity, and excitation spectra. ... Read more

A cell line originated from a patient diagnosed with high-grade serous ovarian carcinoma (HGSOC). ... Read more