Many newly developed anti-cancer treatments rely on identifying cancer unique signatures that can be used to harness the immune system against the tumor. The internal state of cells is represented on their surfaces by Human Leukocyte Antigen (HLA), molecules that bind and display ... Read more

non-small cell lung cancer (NSCLC) has a poor prognosis and low survival rates. Recently developed immunotherapy has revolutionized the therapy for NSCLC, significantly prolonging the overall survival of advanced‑stage patients. NSCLC comprises approximately 85-90% of all known ... Read more

This technology provides a method to identify the full landscape of proteins that are actively being degraded by the proteasome, offering a way to identify novel targets in various biological conditions and contexts. The cell's proteome (protein profile) is constantly changing du... Read more