Proteasome-derived defense peptides (PDDPs) represent a novel class of antimicrobial peptides (AMPs) generated through proteasomal degradation. These peptides disrupt bacterial membranes and provide a cell-autonomous defense mechanism against infections. Sepsis treatment – PDDPs... Read more

MAPP (Mass Spectrometry Analysis of Proteolytic Peptides) is a groundbreaking technology that isolates and identifies proteins actively degraded by the proteasome, offering an unparalleled and direct view of the "active degradome." This innovative approach provides a sensitive an ... Read more