Results for technologies (125)
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RF Resonators for Strong Driving of Nuclear Spins (No. T4-2431)
An RF resonator designed for strong and fast driving of nuclear spins with applications in quantum sensing and microscopy. The resonator is a spiral structure composed of two metallic layers separated by an insulating material.
Integration in quantum sensing toolboxes for addressi...
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19127
Synthetic Antimicrobial Peptides for Selective and Potent Malaria Treatment (No. T4-2408)
Malaria remains a major global health challenge, with increasing resistance to current drugs and limited treatment options that selectively target infected red blood cells.
Applications
Demonstrated potent in vitro activity against P.falciparum with clear selectivity an...
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19146
Computationally Designed Peroxygenases for Selective Terpene Oxyfunctionalization (No. T4-2403)
Terpenes represent the largest class of secondary plant metabolites. Their oxyfunctionalized derivatives, terpenoids, are widely used in the pharmaceutical, flavor, and fragrance industries due to their aromatic properties.
Applications
Fifty computationally designed va...
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19149
A Multistate Memory Cell Based on Electrochromic Metallo-Organic Assemblies (No. T4-2360)
The pressing and ongoing demand to boost chip capacity while simultaneously reducing its size underscores the crucial importance of enhancing memory cell technology. In response to this need, we have innovated a conceptually new memory cell.
The drive towards miniaturization and e...
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18973
AI-Driven Zebrafish Behavioral Tracking for Psychiatric Drug Screening (No. T4-2358)
A high-resolution tracking system for analyzing complex individual zebrafish behaviors in an unconfined environment. By leveraging machine learning, this method provides an accurate model for drug screening with higher relevance to naturalistic behavior, particularly for psychiatric drugs.
...
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18940
Colloidal Synthesis of Micron-Scale Organic Crystalline Spherulites (No. T4-2334)
A controllable method for synthesizing organic, crystalline spherulites from compounds with guanine-based structures.
Paints and coatings
Food coloring
Cosmetics
Plastics
Ink and tattoo pigments
Supplements
Medicine
Toothpaste
Non-toxic
Biocompatible
Can be applied to ...
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19076
Smart Energy Storage Devices with Visual Charge Monitoring (No. T4-2316)
The growing demand for energy devices that store and deliver power and offer additional functionalities, like instant performance monitoring, is evident.
Electrochromic (EC) materials change their optical transparency when voltage is applied. A particularly promising category of E...
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18931
Duster Buster: Endourological Device To Remove Stone Fragments From Kidneys (No. T4-2312)
When performing laser fragmentation (lithotripsy) on kidney or ureteral stones, it is common to have small fragments remain in the kidney. Existing methods for extracting these fragments and "dust" have shown insufficient performance.
Laser fragmentation, or lithotripsy, used to t...
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18913
Aerobic Electrochemical Oxidation of Hydrocarbons (No. T4-2279)
Aerobic oxidation is a chemical reaction in which hydrocarbons such as alkanes or alkenes are oxidized using oxygen as the oxidizing agent.
Saturated and unsaturated hydrocarbons, alkanes and alkenes, respectively, are primary chemicals found in natural gas and formed in petroleum...
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18592
Stirring-Free Scalable Electrosynthesis Enabled by Alternating Current (No. T4-2268)
Electrochemical transformations are unfavorable while using conventional direct current (DC) electrosynthesis. The main reason is the interelectrode mass transfer, which serves as a major limiting factor for the overall efficiency and the process’s selectivity.
The vast majority...
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18649
Sparsity Based Non-Contact Vital Signs Monitoring of Multiple People Via Radar (No. T4-2257)
Current contact-based monitoring devices cause patient discomfort, increase infection risks, and demand significant medical staff time.
Medical Monitoring: Heart rate, respiration, sleep apnea detection, lung function, cardiac diagnostics in hospitals, clinics, and homes.
Workplac...
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18610
Nonlinear Waveform Inversion for Quantitative Ultrasound (No. T4-2254)
Conventional ultrasound brightness-mode images do not provide sufficient contrast for certain anatomical structures and have a poor physical interpretation. This can highly affect the medical diagnosis reliability.
Due to its non-invasive and non-radiating nature, along with its l...
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18751
Transparent Electrodes Based on Carbon Nanotubes (No. T4-2235)
The electrical, optical, and mechanical qualities of transparent conductive electrodes (TCEs) make them ideal for electro-optic applications. However, existing TCEs are costly, inflexible, and their performance is inadequate.
Carbon nanotubes (CNTs) are utilized to produce high-qu...
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18754
Nephrostomy Tube – A New Design to Decrease Dislodgement (No. T4-2230)
The existing nephrostomy tube design, widely used for kidney drainage, presents challenges related to accidental premature extraction, necessitating resource-intensive replacement.
Nephrostomy tubes are vital in managing short- and long-term medical conditions, including ureteral ...
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Yaniv Shilo
18868
Adapters for Targeted Viral Vector-Based Therapies (No. T4-2229)
A major challenge in developing viral-based therapies, such as gene therapies, CAR-T cell immunotherapy, and oncolytic virotherapy, is that the most efficient vectors and viruses are not specific, preventing their direct administration to the patient. Prof.
VSV-G-pseudotyped lenti...
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18691
Anti importin beta1 monoclonal antibody (No. M7-2223)
A highly specific and sensitive anti-Importin b1 (KPNB1) monoclonal antibody. The mAb recognizes an epitope comprising residues 301-320 of human KPBN1 and is highly specific for cytoplasmic KPNB1 in diverse applications.
Importin b1 (KPNB1) is a nucleocytoplasmic transport factor...
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17648
An Improved Single-Cell RNA-Sequencing Method (No. T4-2217)
Single-cell RNA sequencing (scRNA-seq) methods enable the detection of only 10%-15% of the cellular transcriptome, rendering low-expressing genes in the dark.
Applications
WRAP-seq is fully developed
TRAP-seq has a POC of several target genes, and is in validation stage...
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18646
Hyperstable Serum Albumin Variants for Microbial Mass Production (No. T4-2216)
Serum albumins are widely used in medicine, biotechnology, and cultivated meat production. However, they are mostly extracted from animal sources, raising ethical, reproducibility, and scalability concerns.
Applications
Variants of human and bovine serum albumins (HBA, ...
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18682
Radiation Curing Enhancement by Semiconducting Nanoparticles (No. T4-2215)
The curing of polymers by UV light is of great technological importance in, for example, dentistry, advanced manufacturing (3D printing), and various applications such as manufacturing of optical media, biotechnology, and more.
Cationic photo-cured thermosetting polymers, like epo...
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17678
High Throughput Screening Platform For Inhibitors of Viral Membrane Fusion (No. T4-2213)
Enveloped viruses pose significant health risks and lack effective treatments. Inhibiting viral membrane fusion, a crucial step in infection, holds promise for antiviral drug development. Dr.
Enveloped viruses, including SARS-CoV-2, influenza, Nipah virus, Hendra virus, HIV, and E...
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18679
GFP variants (No. M7-2209)
A collection of GFP variants with improved/unique properties, such as increased thermostability, photostability, quantum yield, altered fluorescence lifetime, pH sensitivity, and excitation spectra.
The team led by Prof. Fleishman developed a machine-learning-based approach calle...
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18032
OM-17 cell line (high grade serous ovarian carcinoma) (No. M7-2202)
A cell line originated from a patient diagnosed with high-grade serous ovarian carcinoma (HGSOC).
...
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18314
Green Synthesis of Biocompatible Porous Nanostructured Silica-Composite (No. T4-2201)
Nanostructured silica is a promising material with remarkable properties, such as high porosity, biocompatibility, and stability.
Nanostructured silica is a group of materials composed of silica with a controllable, homogeneous, and functionalized nanosurface.
It was di...
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18137
Enhancing Biofuel Production through Engineered Versatile Peroxidases (No. T4-2197)
The growing need for sustainable biofuel alternatives is challenged by the difficulty of breaking down lignin, a major component of plant biomass.
Applications
36 engineered VPs were designed, with four successfully expressed in yeast. Three candidates demonstrated dive...
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18667
Super Resolution Vascular Ultrasound Imaging for Clinical Diagnostics (No. T4-2194)
Alterations in the microvasculature characterize various pathologies, including cancers and inflammatory diseases (i.e., Crohn's disease). Therefore, precise in vivo microvascular imaging at the capillary level could be a valuable tool for early diagnosis and clinical management.
...
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16721
Splicing ViT Features for Semantic Appearance Transfer (No. T4-2192)
Artificial intelligence (AI) solutions are vastly available for applications such as object segmentation, image detection, visual creation, writing assistance, and many more. There is a continuous quest to improve photograph editing software and existing AI systems.
The demand for...
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18637
Zirconium Doped Ceria Electroceramic with a High Electrostriction Coefficient (No. T4-2180)
Electrostrictive materials can generate large movement under voltage, making them attractive for numerous applications.
Electrostrictors are applicable in every device where voltage-controlled movement is required.
Doping ceria with Zr can increase the electrostriction ...
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18925
MMP14 targeting natural antibodies to treat ovarian cancer (No. T4-2152)
Ovarian cancer is the fifth leading cause of cancer-related death in women. Due to a lack of early detection methods, it is often diagnosed at a late stage, resulting in negligible changes to cure.
Ovarian carcinoma is the most lethal gynecological malignancy and the fifth leading...
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17825
Diagnosis and Treatment of Breast Cancer based on Extracellular Vesicles (No. T4-2145)
Early detection of breast cancer (BC) and monitoring its progression, treatment response, and recurrence are crucial for survival.
Early detection of BC is crucial for successful therapy and survival. Currently, screening commonly relies on mammography, ultrasound, and magnetic re...
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16676
Biodegradable "Fiberglass" for Packing Industry (No. T4-2137)
Conventional plastics are materials with attractive properties but with low recyclability. They also persist in the environment. Furthermore, the plastic waste decomposes into microplastic, which pollutes the soil, the sea, and the air. Therefore new regulations restrict its use.
...
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14756
Novel Combination Therapy For Improved Management of Depression (No. T4-2129)
Psychiatric disorders, especially major depressive disorder (MDD), are leading causes of disability and premature death across the globe, with patients showing a heightened risk of self-harm and suicidal ideation. Prof.
Major depressive disorder (MDD) is the third-leading cause of...
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6097
Reusable Gold Nanostars Substrates for Signal Amplification for Diagnostics (No. T4-2127)
Numerous spectroscopic techniques utilize signal enhancement from surfaces of nanoparticles linked to analyte molecules. However, existing surface-enhanced spectroscopies (SES) are based on solution-based nanoparticles dispersion and are unsuitable for solid substrates. Dr.
Surfac...
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12950
A Method for Vitamin D Production (No. T4-2086)
A sustainable method to produce vegan Vitamin D using the microalga Emiliania huxleyi. This approach enables efficient production of both Vitamin D2 and Vitamin D3, along with additional nutritional values, in a dry biomass form suitable for nutritional supplements.
Nutritional Su...
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18442
Modulating Weight Gain and Loss by Understanding the Mechanism of Smoking Related Weight Changes (No. T4-2078)
A new approach to prevent weight gain during smoking cessation (SCWG) focuses on the gut microbiome and metabolites like dimethylglycine (DMG) and acetylglycine (ACG).
Modalities for Weight Management: Development of treatments targeting these metabolites to aid in weight loss.
...
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17357
Enhanced Anti-PD-L1 Immunotherapy (No. T4-2059)
Immunotherapy has revolutionized cancer treatment by activating the immune system to attack tumor cells. However, notable limitations remain, including differential responses between individuals and cancer types. Dr.
Checkpoint inhibitors are drugs used to activate the immune syst...
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17039
Peptides for Treating Alzheimer's Disease (No. T4-2057)
Alzheimer's Disease (AD) is an age-associated neurodegenerative disorder characterized clinically by a decline in cognitive function. It is the most common type of dementia, with 5.8 million Americans living with AS in 2020.
Alzheimer's disease (AD) is an age-associated, irreversi...
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Ruth Arnon
Faculty of Biology
6160
Spin Current and Magnetoresistance from the Orbital Hall Effect (No. T4-2053)
The Spin Hall Effect (SHE) generates spin current, spin torque, and magnetoresistance and is extensively used in spintronic devices, such as memory devices, magnetic sensors, and data storage media. However, strong SHE behavior mainly exists in heavy and expensive metals.
The Spin...
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18700
YotiCurl Ureteral Stent (No. T4-2052)
Ureteral/kidney stones are a very common disease, affecting millions. In some cases, the stones may cause an obstruction that requires inserting a single-use ureteral stent to maintain urine flow.
Ureteral/kidney stones are a frequent disease estimated to affect between 10-15% of ...
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18871
Coupling of Alternating Current to Transition – Metal Catalysis (No. T4-2050)
The coupling of transition-metal to photoredox catalytic cycles through single-electron transfer steps has become a powerful tool in the development of catalytic processes.
Transition-metal catalysis is one of the most common forms of catalysis. However, the number of possible tra...
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18308
Protein coupling using cystein-free inteins (No. T4-2039)
Traceless covalent modification of proteins, including joining peptides or adding chemical groups, is extremely useful for numerous applications in chemical biology, protein chemistry, and biotechnology.
Modifying or joining proteins with other proteins/ peptides/chemical groups i...
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6862
Cell-free microRNA as a Prognostic Biomarker for Amyotrophic Lateral Sclerosis (ALS) (No. T4-2038)
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder of the human motor neuron system, for which no effective treatment exists.
ALS is a relentless neurodegenerative syndrome of the human motor neuron system, for which no curative treatment exists. It is...
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6115
Frontotemporal Dementia Diagnosis Using Circulating microRNA Biomarkers (No. T4-2037)
Frontotemporal dementia (FTD) is a heterogeneous neurodegenerative disorder characterized by frontal and temporal lobe atrophy, typically manifesting with behavioral or language impairment.
FTD is the second most common form of dementia, after Alzheimer’s disease below the age o...
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6082
Scarless CRISPR-mediated Genome Editing (No. T4-2036)
CRISPR-Cas9 is a widely-used tool for genome editing; however, it is very inefficient and often requires the addition of selection markers, forcing the introduction of foreign DNA elements.
CRISPR-Cas9 method, while promising, is currently inherently inefficient and requires selec...
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6112
Safer CAR-T Cell Platform (No. T4-2033)
Chimeric Antigen Receptor (CAR)-T Cell Therapy is a personalized treatment for cancer in which the patient's T cells are genetically engineered to express a synthetic receptor that binds a tumor antigen.
CAR-T Cell Therapy is a cutting-edge immunotherapy modality with a global mar...
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6124
Cell Surface Modification with Synthetic Receptors (No. T4-1961)
Technologies that target cells or modify their behavior are of great interest to improve diagnostic, therapeutic, and imaging platforms.
Cell surface proteins are key mediators of cell responses to changing environments. They are naturally regulated by dynamic structure, expressio...
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7150
Unique Fingerprinting Using Strain in Nanodiamonds (No. T4-1957)
Fluorescent nanodiamonds are nanoparticles (less than 100 nanometers) made of diamonds that have been engineered to emit fluorescent light. They are used in various applications, including biological imaging and sensing.
Fluorescent markers are site-labeled markers in nanotechnolo...
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18706
Carbon Nanotubes - Polymer Composites for Improved Mechanical and Electrical Properties (No. T4-1953)
The superior mechanical and electrical properties of carbon nanotubes (CNTs) are uniquely advantageous for enhancing polymer composites' mechanical and electrical properties. However, CNTs usually heavily bundle.
Markets continuously search for stronger, more durable, lightweight,...
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18922
Small Molecules for Treatment of Huntington's Disease and Related Disorders (No. T4-1947)
Trinucleotide repeats expansion disorders (TREDs) are a set of diseases in which repetitions of short DNA segments (three nucleotides) occur and accumulate in the genome.
TREDs are a group of human diseases in which repeats of three nucleotides accumulate in the genome.
...
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6193
Treatment for Drug-Resistant Non-Small Cell Lung Cancer (No. T4-1944)
Non-Small Cell Lung Cancer (NSCLC) is a very common type of cancer, and despite currently available therapies, is one of the deadliest due to the emergence of drug resistance, which results in tumor recurrence.
Lung cancer is one of the most deadly and common types of cancer in th...
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6025
Artificial Pancreas (No. T4-1942)
The alarmingly sharp increase in type 1 diabetes mellitus incidence in recent years has been coupled with a marked rise in the development of closed-loop systems aimed at continuously monitoring blood glucose levels, predicting glucose behavior and delivering adjusted insulin doses.
...
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5752
New Antiviral Drugs from Bacterial Natural Products (No. T4-1934)
The increasing incidence of viral infections across the globe is driving the demand for antiviral drugs. Prof. Rotem Sorek and his team identified a new family of bacterial enzymes that produce various nucleotide analogs with antiviral properties (Bernheim, Nature 2021).
The incre...
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12514
Higher Efficiency of CRISPR Gene Editing Using Chimeric Cas9 (No. T4-1930)
CRISPR-Cas9 is a powerful tool for genome editing, widely used for basic research and the development of treatments for genetic diseases. However, its efficiency is currently limited.
CRISPR-Cas9 is a powerful tool for genome editing that allows researchers to modify genomes easil...
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6024
Anti-LOX/HSP70 Treatment for Duchenne, Fibrosis and Cancer (No. T4-1913)
Duchenne muscular dystrophy (DMD) is a disease that affects approximately 1 in 3,500 boys with a life expectancy of ~26 years.
Duchenne muscular dystrophy (DMD) is a disease that causes progressive muscle weakness, loss of skeletal and heart muscle tissue, degeneration, and eventu...
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6026
Iron Catalyzed Ring-Opening Metathesis Polymerization (ROMP) (No. T4-1905)
The olefin metathesis reaction is among the most important catalytic carbon-carbon double bond formation reactions. The most widely used catalysts for this reaction are Mo- and Ru- carbene complexes which are expensive and toxic 1.
Mo- and Ru-carbene catalysts are the most common ...
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6199
Inorganic Nanotubes/Polymer Composites for 3D Printing (No. T4-1900)
Biocompatible polymers commonly used in the orthopedic and cosmetic prosthetics, cardiovascular and dental implants and food packaging industries often suffer from poor mechanical properties and thermal stability, limited dimensionality and short shelf-life as compared to their metal compara...
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5737
GreenTap - A Method for Stimulating Production and Extraction of Metabolites in Plants (No. T4-1894)
A method for inducing and extracting valuable plant metabolites without damaging the plant or interfereing with compound formation.
Production of Bioactive Compounds: Increases yield of plant metabolites used in pharmaceuticals, food, and cosmetics.
Novel Metabolite Discovery: Pro...
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6029
A Sustainable Process for Phenol Production (No. T4-1892)
Phenol is an important industrial commodity used as a precursor to many useful compounds.
The cumene hydroperoxide process, which is the most commonly used phenol production process nowadays, is both complicated, with low per pass cumene conversion and is producing acetone as a by...
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5728
Universal CAR-Ts for Treating Cancer (No. T4-1884)
Chimeric Antigen Receptor T-Cells (CAR-Ts) are one of the revolutionary technologies of the twenty-first century, invented by Prof. Zelig Eshhar at the Weizmann Institute of Science.
The group of Prof. Eshhar has developed a method for an adoptive cell therapy, such that cells fro...
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Zelig Eshhar
Faculty of Biology
5722
Targeting CD74 for Oncology Application or to Generate Improved Hematopoietic Stem Cells Generation (No. T4-1874)
A potential method of generating hematopoietic stem cells for transplantation by inhibiting CD74.
Hematopoietic stem cells (HSCs) originate in the bone marrow and are the progenitors of all hematopoietic cells. HSCs have the capacity to both self-renew and to differentiate, and t...
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5716
Optical Bus for a Multi-Core Processor (No. T4-1863)
A compact on-chip optical layer that replaces traditional wiring in multi-core processors using silicon photonics. This innovative approach significantly reduces power consumption, heat generation, and space requirements, enabling higher core densities and improved inter-core communication.
...
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5704
Super-Resolution Using Unsupervised Deep Internal Network (No. T4-1850)
Optical and dimensional limitations of images can be partially overcome today using signal enhancement technologies which typically rely on supervised, deep-learning methods.
Signal enhancement of corrupted input collected under suboptimal conditions, poses multiple challenges, in...
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5701
Composite Functional Metasurfaces for Multispectral Achromatic Optics (No. T4-1845)
A new technology for producing flat optical components based on optical metasurfaces. These components can potentially serve high resolution imaging, spectrometry, light processing and beam shaping devices.
The proposed technology can be used to generate a wide variety of novel ...
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5689
Secure Search of Encrypted Cloud Data (No. T4-1840)
Searchable symmetric encryption with practical big-data performance and strong security
Highlights
...
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5683
Highly Selective Fluorescent Biosensor for Labeling His-Tagged Proteins in a Specific Conformation (No. T4-1834)
A rapid, label-free biosensor for detecting specific conformation of His-tag labeled proteins, accessible for use in both academic- and commercial-R&D was invented at the Weizmann Institute of Science.
The biosensor presented here is comprised from three main molecular-compone...
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5677
A Method to Identify Actively Degraded Proteins (No. T4-1832)
MAPP (Mass Spectrometry Analysis of Proteolytic Peptides) is a groundbreaking technology that isolates and identifies proteins actively degraded by the proteasome, offering an unparalleled and direct view of the "active degradome." This innovative approach provides a sensitive an
...
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6030
Inertial NEMS for Nanosensor Applications Based on Inorganic Nanotubes (No. T4-1828)
Inertial sensors for motion detection are being incorporated into an increasing number of portable devices, including diverse IoT applications, mobile phones, wearable electronics, automotive systems and medical diagnostic sensors.
Current microelectromechanical system (MEMS) fabr...
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5674
Homogeneous Dispersion of CNT Composites for Improved Conductivity, Bucky Papers (No. T4-1809)
Battery and capacitor electrode technologies available in the industry today, are struggling to keep up with rapidly advancing applications that require high power and energy density such as electric vehicles, solar cells and telecommunications systems.
The growing need to provide...
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5662
Microbiome-Based Prediction, Diagnosis, and Treatment of Relapsing Obesity (No. T4-1805)
A novel gut microbiome-based method has been developed to predict and prevent weight regain after weight loss.
Predictive Diagnostic Tool: Provides a microbiome-based test to identify individuals at high risk of post-diet weight regain.
Personalized Approach: Uses a mac...
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5659
Treating Drug-Resistant Lung Cancer Using a Combination of Antibodies (No. T4-1774)
A novel method to treat tyrosine kinase inhibitor (TKI) resistant cancer by using a combination of three antibodies that target EGFR (ERBB1), HER2 (ERBB2), and HER3 (ERBB3) receptors.
The ErbB/HER family of receptor tyrosine kinases includes epidermal growth factor receptor (EGFR...
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5635
Carbon fixing bacteria (No. T4-1736)
Prof. Ron Milo and his team have engineered a bacteria (E. coli) to fix atmospheric CO₂, converting it into organic biomass. This breakthrough synthetic biology approach enables E.
Potential Precision Fermentation Platform: A modular platform for producing various chemicals with...
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5608
Green Chemistry for Ketones and Aldehydes Production (No. T4-1722)
Our technology provides a new type of oxidative cleavage reaction of organic compounds with highly selective product formation.
The realization that many processes practiced on a large scale were detrimental to the environment led to a movement of reshaping the science of organic ...
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5596
Highly Selective Optical Biosensors for Proteins in Biological Samples, with Excellent Signal-to-Noise Ratio (No. T4-1689)
Sensing the levels of protein-based biomarkers in biological samples is crucial for diagnosis of various diseases including cancer.
Applications
Detection of proteins in biological samples for medical diagnostics
Fluorescent detection of His-tag or GST labeled proteins for imaging...
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5587
Preventing Infections Using Lipid Based Molecules (No. T4-1673)
Sphingosine (SPH), a natural bactericidal agent which acts as a part of the human innate immune system in the skin, was found to be an effective treatment and prophylaxis for bacterial lung infections in cystic fibrosis (CF) mice.
Cystic fibrosis (CF) is caused by mutations in the...
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5584
Recycling of Precious Metals via an Efficient Process with no Toxic Byproduct (No. T4-1670)
Platinum group metals (PGM) are well-known precious metals that play an important role in many industrial applications as catalysts. Current methods for their recycling are not efficient, require extreme conditions, and involve toxic reagents or byproducts. Prof.
PGM, e.g., platin...
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13574
Magnetic resonance imaging (MRI) Of Tissue Fibrosis without Contrast Agent (No. T4-1665)
Cardiac fibrosis is a scarring event in the cardiac muscle that causes abnormalities in cardiac function and significantly increases the risk of sudden cardiac death.
Myocardial fibrosis is associated with worsening ventricular systolic function, abnormal cardiac remodeling, and i...
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5575
Optimized MAGE-A1 specific TCR (No. T4-1662)
Using affinity maturated TCRs to generate reactive T cells
Immunotherapy, that is the use of the immune system to treat cancer, is currently a leading candidate in the combat against cancer.
This technology presents a new method of increasing the affinity of a TCR to i...
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5572
Repurposing of a Small Molecule Drug for ALS Treatment (No. T4-1632)
Amyotrophic Lateral Sclerosis (ALS) remains an incurable neurodegenerative disease, in need of innovative treatment options. Prof. Eran Hornstein and his team identified microRNAs (miRNA) as pivotal regulators of ALS progression.
ALS is a progressive neurodegenerative disorder cau...
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18887
Novel MRI Contrast Agent (No. T4-1604)
Novel reporter gene for magnetic resonance imaging applications.The ability to image the duration and location of gene expression in vivo and noninvasively is imperative for the future of biology and clinical medicine.
Non-invasive imaging of gene expression in transgenic mice mod...
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5545
A Novel Database to Reduce Unsuccessful Cloning in E. Coli by Detection of Toxic Genes (No. M7-1576)
Synthetic genes are commonly used in academic and industrial applications, however in many cases these said genes can be toxic when inserted into the ubiquitously used E. coli. This is problematic as time and money is wasted on attempts to generate genes that will not function in E. coli.
...
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5530
Inorganic Fullerene Coating For Medical Devices (No. T4-1566)
Implantable or insertable medical devices must be made of materials with unique properties in addition to biocompatibility to address potential damage from the physiological environment and to maintain their effectiveness over time.
Implantable or insertable medical devices must b...
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5521
Green Catalytic Formation of Alcohols, Amines, Amides, Imines and Esters under Mild Conditions (No. T4-1551)
In recent years, complexes based on cooperating ligands have exhibited remarkable catalytic activity. These ligands can cooperate with the metal center by undergoing reversible structural
changes in the processes of substrate activation and product formation.
Amines, alcohols, am...
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5512
Highly Sensitive Nanoscale Scanning Magnetic and Thermal Sensor (No. T4-1481)
A nanoscale Superconducting Quantum Interference Device (SQUID) on Tip (SOT) that enables high spatial, magnetic, and thermal resolution for local imaging.
Scanning Probe Microscope
Cryogenic Thermal Imaging (mK Temperatures)
Metrology Tools for Quantum Circuits
Imaging of Electri...
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5482
High-Performance Electrochromic Devices (No. T4-1380)
High-performance electrochromic materials that exhibit a practical combination of low-voltage operation and efficient color-switching, as well as long-term stability have been developed by the group of Prof. van der Boom.
The trends towards energy efficiency, comfort and privacy a...
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5458
Mouse IgE and Anti-Mouse IgE Monoclonal Antibodies (No. M7-1270)
Monoclonal antibodies to IgE Description: Rat monoclonal anti-IgE antibodies that was generated by fusion of plasmacytoma (84.1C) or myeloma (EM953) cells with splenocytes of rat immunized with purified murine IgE mAb.
...
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Zelig Eshhar
Faculty of Biology
5452
Cholesterol Antibodies (No. T4-1267)
Description: Monoclonal antibodies specific for cholesterol/ceramide-rich domains (clones 405F, 14F, 499F) and cholesterol micro-domains (clones 36A1, 5881) in cell membranes. Originally raised against an artificial monolayer of lipid mixtures in, and were shown to specifically label the ab...
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5449
Blood Test to Identify People at High Risk for Lung Cancer (No. T4-1033)
A novel diagnostic test to identify individuals with increased risk of lung cancer
Lung cancer is the number one killer among cancers, with 160,000 deaths/year in the USA and 1.6 million/year worldwide. Early detection of lung cancer increases 5-year survival rate from 4% to 54%....
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5428
Escherichia coli UTL2 (No. M7-358)
Escherichia coli UTL2 Description: A "leaky" strain of E. coli, which is significantly more susceptible to cytotoxic agents. UTL2 holds a mutation in the galU gene causing an impaired outer membrane.
...
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5425
Anti-Mast cell Function-associated Antigen (MAFA) monoclonal antibody (No. M7-320)
320 - Monoclonal antibody G63 Description: Monoclonal antibodies to MAFA (Mast cell Function-associated Antigen), originally raised against intact rat RBL-2H3 cells.
...
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5422
Anti-Runx-3 monoclonal antibody (No. M7-306)
Monoclonal antibody to Runx-3 Description: Monoclonal antibody to Runx-3 raised against the Runx3 peptide TPSTPSPRGSLSTTSHF. Available clones: 62, H8.
...
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5416
Anti-Estrone-3-Glucuronide monoclonal antibody (clones: 155B3, 8A3) (No. M7-276)
Monoclonal antibodies raised against estrone-3-glucuronide-BSA. Available clones: 8A3 (Rat, IgG2a), 155B3. Estrone-glucuronide is the dominant metabolite of estradiol. Used as one reference method for determining ovulation.
Monitoring ovarian function by the simultaneous t...
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5413
Anti-Estrone-3-Glucuronide monoclonal antibody (No. M7-275)
Monoclonal antibodies raised against estrone-3-glucuronide-BSA. Available clones: 8A3 (Rat, IgG2a). Estrone-glucuronide is the dominant metabolite of estradiol. Used as one reference method for determining ovulation.
Monitoring ovarian function by the simultaneous time-resolved fl...
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5410
Anti- estrone-3- glucuronide monoclonal antibody (No. M7-273)
Betatypic anti-idiotypic antibody raised against anti- estrone-3- glucuronide (clone 8A3). Available clone: 7C1.
Monitoring ovarian function by the simultaneous time-resolved fluorescence immunoassay of two urinary steroid metabolites.
Barnard G, Kohen F.Clin Chem. 1998 J...
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5404
499F (No. M7-265)
Monoclonal antibodies specific to cholesterol/ceramide mixture
Description: Monoclonal antibodies specific for cholesterol/ceramide-rich domains (clones 405F, 14F, 499F) and cholesterol micro-domains (clones 36A1, 5881) in cell membranes.
...
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Luana Scheffer
Chemistry
5401
Monoclonal Antibodies Specific to Cholesterol/Ceramide Mixture Clone (No. M7-263)
Originally raised against an artificial monolayer of lipid mixtures in, and were shown to specifically label the above domains in different cell membranes. Reference: Scheffer L, Futerman AH, Addadi L. 2007. Antibody labeling of cholesterol/ceramide ordered domains in cell membranes.
...
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Luana Scheffer
Chemistry
5398
Monoclonal Anti-Caspr Antibody (Mab#275) (No. M7-259)
259 - Monoclonal antibody to Caspr Description: Monoclonal antibody to Caspr (Mab275), raised against the extracellular domain of Caspr.
...
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5392
Monoclonal Anti-Ermin Antibody (Mab#160) (No. M7-258)
258 - Monoclonal antibody to Ermin Description: Monoclonal antibody to Ermin (MAb160) raised against purified GST–Ermin (residues 1–261).
...
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Damian Brockschnieder
5389
Monoclonal Anti-Gliomedin Antibody (Mab#94) (No. M7-257)
257 - Monoclonal antibody to Gliomedin Description: Monoclonal antibody to Gliomedin (MAb 94) raised against a synthetic peptide corresponding to amino acid residues 273–287 (CVIPNDDTLVGRA), present in the extra cellular region of Rat Gliomedin.
...
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5386
Anti-IgE monoclonal antibody (No. M7-185)
Monoclonal antibodies to IgE Description: Rat monoclonal anti-IgE antibodies that was generated by fusion of plasmacytoma (84.1C) or myeloma (EM953) cells with splenocytes of rat immunized with purified murine IgE mAb.
...
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Michal Baniash
Zelig Eshhar
Faculty of Biology
Tova Waks
Faculty of Biology
5365
Anti-Phospho-ERK (PY193 or PT115) Monoclonal Antibodies (No. M7-176)
176-177 - Monoclonal antibodies to phospho-ERK/Map Kinase Description: Monoclonal antibodies raised against peptides containing the 11 amino acids, HTGFLTEYVAT, corresponding to the ERK activation loop either Tyr -phosphorylated (ERK-PY193), or Thr-phos
...
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5356
Clone - 1E11 (No. M7-148)
Monoclonal antibodies for peptide and steroid hormones Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics.
...
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5350
Anti-Human chorionic gonadotropin (hCG) monoclonal antibody (No. M7-147)
Monoclonal antibodies raised against bhCG. Available clones: 1D5 (IgG1) .Human chorionic gonadotropin (hCG) is a hormone produced by the syncytiotrophoblast, a component of the fertilized egg, after conception.
...
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5347
Clone 1E11 Progesterone (No. M7-146)
Anti-progesterone. Monoclonal antibody raised against position 11 of progesterone (Clone 1E11). It is very specific for progesterone.Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
...
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9580
Anti-oestradiol-6-carboxymethyl oxime monoclonal antibody (No. M7-141)
Monoclonal antibodies to estradiol Description: Monoclonal antibodies raised against oestradiol-6-carboxymethyl oxime-BSA. Available clones: 2F9 (Rat, IgG2a), 15 (IgG2b), 8D9 (IgG2a).
Direct chemiluminescence immunoassay for estradiol in serum. De Boever J, Kohen F, Usanachitt C, ...
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5335
Anti-progesterone-7 monoclonal antibody (No. M7-138)
Monoclonal antibodies raised against position 7 of progesterone (clone 2H4), Rat IgG1. Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food produc...
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5332
Human T3N1M1 prostatic adenocarcinoma tissue for xenograft (No. M7-132)
WISH-PC frozen tissue samples
...
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Zelig Eshhar
Faculty of Biology
5329
Anti-idiotypic antibody against anti-Sulfamethazine (12E12) (No. M7-130)
Betatypic anti-idiotypic antibody raised against anti Sulfamethazine –KLH (clone 21C7). Available clone: 12E12.
Generation of an anti-idiotypic antibody as a surrogate ligand for sulfamethazine in immunoassay procedures/
...
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5326
Anti-testosterone 3-(0- carboxymethyl)oxime-BSA monoclonal antibody (No. M7-119)
Rat monoclonal antibodies raised against testosterone 3-(0- carboxymethyl)oxime-BSA. Available clones: 5F2, 5A4.Testosterone is the principal male sex hormone and an anabolic steroid.
Preparation of monoclonal antibodies able to discriminate between testosterone and 5 alpha-dihydr...
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5317
Anti-Biotin Antibody (No. M7-116)
Monoclonal anti-biotin antibody (clone F1). Very specific for biotin.
Preparation and properties of anti-biotin antibodies.
...
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5308
Anti-Sulfamethazine monoclonal antibody (No. M7-115)
Monoclonal antibody to Sulfamethazine (SMZ) Description: Rat monoclonal antibodies raised against Sulfamethazine-BSA. Available clone: 21C7, IgG1. Sulfamethazine is an antibacterial agents commonly given to food animals (swine, fishetc.) to prevent disease and maximize production.
...
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5305
An endothelial-adipose cell line derived from a murine bone marrow stroma (14F1.1) (No. M7-103)
103 - Bone marrow derived stroma cell line 14F1.1
Description: An endothelial-adipose cell line derived from a murine bone marrow stroma.
...
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5302
LTC4 (6E7) (No. M7-101)
Rat monoclonal antibodies raised against Leukotriene C4-KLH. Available clone: 6E7 (IgG1). Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.
...
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5299