Chemistry and Nanotechnology

Production of Amines from Alcohol and Ammonia (No. T4-1507)

Lead Researcher: David Milstein


Amines are widely used in the production of numerous products for multiple industries and their use is expected to increase. Global amines market is expected to reach over $14 billion by 2020, with an average annual growth of 3.5%. Primary amines are most useful in the larger markets of ethanolamines and fatty amines.Current synthetic methods require harsh reaction conditions, are non-specific and generate toxic waste. The outlined technology utilizes a novel catalyst to synthesize primary amines in a simple single-step fashion directly from alcohols and ammonia.

  •  Production of primary amines for numerous industries (agrochemicals, surfactants, personal care, water treatment, fine chemicals, plastics, dyes, pigments, food additives and pharmaceuticals)
  • Mild reaction conditions
  • Single step synthesis
  • High yields
  • No solvent required
  • No toxic reagents or by-products
  • Ecologically and economically beneficial
Technology's Essence

Amines are a very important family of compounds used in multiple industries. The presented technology uses selective catalytic synthesis of primary amines from primary alcohols and ammonia. This simple, one-step, easily applicable reaction delivers primary amines in good yields, in addition to valuable environmental and economic advantages.