Monoclonal Anti-Caspr Antibody (Mab#275) (No. T4-259)
Lead Researcher: Prof. Elior Peles
259 - Monoclonal antibody to Caspr Description: Monoclonal antibody to Caspr (Mab275), raised against the extracellular domain of Caspr. Caspr is a contactin-associated protein, part of the neurexin family of proteins. It lies in the paranodal section of the myelin sheath and has a role in myelin sheath attachment along with contactin. May be glycosylated.
Reference: Poliak S1, Gollan L, Martinez R, Custer A, Einheber S, Salzer JL, Trimmer JS, Shrager P, Peles E. 1999. Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels. Neuron. 24(4):1037-47.