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Inhibitory Proteins for 20S Proteasome Regulation as Cancer Treatment (No. T4-2065)
Proteasomal protein degradation is crucial in maintaining cellular integrity and in regulating key cellular processes including cell cycle, proliferation and cell death.
The protein degradation machinery plays a critical role in the maintenance of cellular homeostasis, preventing ...
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6139
Modulating Protein Degradation through COP9 Signalosome regulation (No. T4-1923)
A potentially therapeutic method to interfere with CSNAP activity, a key negative regulator of protein degradation.
Protein degradation is one of the most essential mechanisms regulating the proteome and its responses to stimuli. The process is largely mediated by E3 ligases, whi...
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18406