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Covalent Chemistry Platform for Diagnostics and Drug Discovery (No. T4-2045)
delivery and activation of drugs or probes is of great importance in therapeutics, diagnostics, and research. For instance, selective delivery/activation of anti-cancer drugs to tumor cells is crucial for their efficacy and reduced side effects.
Targeted delivery and/or activation...
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6106
Covalent Inhibitors for Treatment of Inflammation and Neurodegeneration (No. T4-1880)
C-Jun NH2-terminal kinase (JNK) plays an integral role in many cellular processes and is associated with the pathophysiology of a number of neurological, inflammatory, and autoimmune diseases.
The JNK signaling cascade plays an integral role in the pathology of several neurodegene...
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6109