The development of kinase inhibitors to treat inflammatory diseases was proved beneficial, however, designing specific inhibitors with minimal side effects and prolonged efficacy is challenging as drug resistance often develops. Inflammatory diseases include a wide variety of cond... Read more

Inhibition of Nuclear Entry of MAPK Cascade Proteins as a Novel Mechanism for Treating Cancer ERK is a major signaling molecule, which plays a driving role in various pathologies, particularly cancer. When not activated ERK is localized to the cytoplasm. The peptide in... Read more

176-177 - Monoclonal antibodies to phospho-ERK/Map Kinase ... Read more

176-177 - Monoclonal antibodies to phospho-ERK/Map Kinase Description: Monoclonal antibodies raised against peptides containing the 11 amino acids, HTGFLTEYVAT, corresponding to the ERK activation loop either Tyr -phosphorylated (ERK-PY193), or Thr-phos ... Read more