The Anti-JUNV GP1 monoclonal antibody specifically recognizes the receptor-binding domain (GP1) of the Junín virus glycoprotein complex (GPC). Developed in mice immunized with recombinant JUNV GP1, this antibody exhibits high affinity (KD ≈ 42 nM) and potent neutralizing activity (IC₅₀ = 11 ng/ml) by targeting the transferrin receptor-1 (TfR1) binding site on GP1.

Applications: ELISA; FACS, Immunoprecipitation, Immunohistochemistry, neutralization

Antigen/Gene or Protein Targets: GP1 from JUNV

Reactivity: Human

Host: Chimera: constant domains – Human, Variable domains – Mouse

Immunogen: portions of GP1 from JUNV (amino acids 77 to 246 of GPC) (see publication for details).

Subclass: IgG1

Molecular weight (in kDa): ~150kDa