Results for technologies (4)
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AI-Powered Deep Phenotyping for Precision Drug Development (No. T4-2443)
Understanding disease biology at the subcellular level is key to precision medicine.
High-content phenotypic screening of therapeutic compounds
Mechanistic insights into drug-induced subcellular effects
Discovery of disease-specific organellar biomarkers
Detects subtle,...
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19425
Cell-free microRNA as a Prognostic Biomarker for Amyotrophic Lateral Sclerosis (ALS) (No. T4-2038)
ALS is a severe neurodegenerative disorder with no cure and highly variable disease progression, which complicates clinical trial design and therapeutic development.
Prognostic tool – Predicts disease progression in ALS patients
Clinical trial optimization by patient stratificat...
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6115
Circulating microRNA Biomarkers for Early Frontotemporal Dementia Diagnosis (No. T4-2037)
Frontotemporal dementia (FTD) is difficult to diagnose due to overlapping symptoms with other neurodegenerative disorders, often leading to delays in treatment and clinical trial enrollment.
Early and accurate FTD diagnosis – Reduces misdiagnosis and diagnostic delays
Clinical t...
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6082
Repurposing Enoxacin: A Novel Therapeutic Strategy Targeting miRNA Biogenesis in ALS (No. T4-1632)
A novel therapeutic strategy for Amyotrophic Lateral Sclerosis (ALS) targets impaired microRNA (miRNA) biogenesis—a key molecular defect found in both sporadic and familial ALS.
Treatment of ALS
Repurposes an FDA-approved drug, reducing development time and regulato...
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18887