LTC4 (6E7) (No. T4-101)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes:  101 – Monoclonal antibody to LTC4 Description: Rat monoclonal antibodies raised against Le ... Read more

An endothelial-adipose cell line derived from a murine bone marrow stroma (14F1.1) (No. T4-103)

Scientist: Dov Zipori

Summary: 103 - Bone marrow derived stroma cell line 14F1.1 Description: An endothelial-adipose cell line derived from a murine bone marrow stroma. Reference: Zipori D, Toledo J, von der Mark K. 1985. Phenotypic heterogeneity among stromal cell lines from mouse bone marrow disclosed in their extracellular matrix composition ... Read more

Anti-Sulfamethazine monoclonal antibody (No. T4-115)

Scientist: Fortune Kohen

Summary:  Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.Leukotrienes:   Veterinary drugs: § 115 - Monoclonal antibody to Sulfamethazine (SMZ) Description: Rat mon ... Read more

Anti-Biotin Antibody (No. T4-116)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.  Biotin: §  116, 142 – Monoclonal antibody to Biotin           Description: Monoclonal antibod ... Read more

Anti-Digoxin monoclonal antibody (No. T4-117)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes:   Drugs:  117 – Monoclonal antibody to Digoxin - Description: Rat monoclonal antibodies ... Read more

Anti-Buserelin monoclonal antibody (No. T4-118)

Scientist: Fortune Kohen

Summary:  Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.Leukotrienes:  Drugs: §  118 - Monoclonal antibody to Buserelin      Description: Rat monoclonal anti ... Read more

Anti-testosterone 3-(0- carboxymethyl)oxime-BSA monoclonal antibody (No. T4-119)

Scientist: Fortune Kohen

Summary: Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. Rat monoclonal antibodies raised against testosterone 3-(0- carboxymethyl)oxime-BSA. Available clones: 5F ... Read more

Anti-Follicle-stimulating hormone (FSH) monoclonal antibody (No. T4-120)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies raised against bFSH. Available clone: 1G12. Follicle-stimulating hormone (FSH) is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation and reproductive processes of the body.Reference: Somjen D1, Tordjman K, Kohen ... Read more

Anti-oestradiol-6- carboxymethyl oxime monoclonal antibody (No. T4-127)

Scientist: Fortune Kohen

Summary: Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. Monoclonal antibodies raised against oestradiol-6- carboxymethyl oxime-BSA. Available clones: 2F9 (Rat, I ... Read more

Anti-idiotypic antibody against anti-Sulfamethazine (12E12) (No. T4-130)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes:   Veterinary drugs: 130 - Anti-idiotypic antibody against anti-Sulfamethazine  Description: B ... Read more

Human T3N1M1 prostatic adenocarcinoma tissue for xenograft (No. T4-132)

Scientist: Zelig Eshhar

Summary: WISH-PC frozen tissue samples Description: Neuroendocrine xenograft model of human prostatic small cell carcinoma cancer. Provides a source to study the involvement of neuroendocrine cells in the progression of prostatic adenocarcinoma and can serve as a novel model for the testing of new therapeutic strategies f ... Read more

Anti-progesterone-7 monoclonal antibody (No. T4-138)

Scientist: Fortune Kohen

Summary: Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. Monoclonal antibodies raised against progesterone-7- carboxythio thioether-BSA (clone 2H4, Rat IgG1) and ... Read more

Anti-oestradiol-6-carboxymethyl oxime monoclonal antibody (No. T4-141)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for peptide and steroid hormones Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.   127, 274, 141 – Monoclonal antibodies to estra ... Read more

F4 (No. T4-142)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.   Biotin:  116, 142 – Monoclonal antibody to Biotin - Description: Monoclonal antibodies raised against ... Read more

Clone 1F5 (No. T4-143)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes: Drugs: 143 - Monoclonal antibody to Medroxy-progesterone-acetate - Description: Rat monoclona ... Read more

Clone 8B6 (No. T4-144)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.Leukotrienes:  Drugs: §  144 - Monoclonal antibody to RU-486 Description: Rat monoclonal antibodies raised ... Read more

Anti-Human chorionic gonadotropin (hCG) monoclonal antibody (No. T4-147)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies raised against bhCG. Available clones: 1D5 (IgG1), 1E11 (IgG2b).Human chorionic gonadotropin (hCG) is a hormone produced by the syncytiotrophoblast, a component of the fertilized egg, after conception.Monoclonal antibodies for peptide and steroid hormones Due to their high specificity and sen ... Read more

Clone - 1E11 (No. T4-148)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for peptide and steroid hormones Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. Peptide Hormones:  147-148 - Monoclonal antibody t ... Read more

Anti-7-(O)-carboxymethyl formononetin monoclonal antibody (No. T4-155)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.  Isoflavones: §  155 – Monoclonal antibody to 7-(O)-carboxymethyl formononetin   Description: 7-(O)-ca ... Read more

Anti-Phospho-ERK (PY193 or PT115) monoclonal antibodies (No. T4-176)

Scientist: Rony Seger

Summary: 176-177 - Monoclonal antibodies to phospho-ERK/Map Kinase Description: Monoclonal antibodies raised against peptides containing the 11 amino acids, HTGFLTEYVAT, corresponding to the ERK activation loop either Tyr -phosphorylated (ERK-PY193), or Thr-phosphorylated (ERK-PT115). ERK belongs to the family of mitogen-a ... Read more

ERK-PT115 (No. T4-177)

Scientist: Rony Seger

Summary: 176-177 - Monoclonal antibodies to phospho-ERK/Map Kinase Description: Monoclonal antibodies raised against peptides containing the 11 amino acids, HTGFLTEYVAT, corresponding to the ERK activation loop either Tyr -phosphorylated (ERK-PY193), or Thr-phosphorylated (ERK-PT115). ERK belongs to the family of mitogen-a ... Read more

Anti-Galactin 8 monoclonal antibody (No. T4-181)

Scientist: Yehiel Zick

Summary: Description: Monoclonal antibody to Galectin-8 (clone 106.1). Galectin-8 is a secreted, integrin-binding protein, part of a mammalian lectins family.  Galectin-8, also known as Prostate Cancer Tumor Antigen-1 (PCTA-1) is highly expressed in human prostate cancer.  It was shown to trigger the transcription of a u ... Read more

Anti-IgE monoclonal antibody (No. T4-185)

Scientist: Zelig Eshhar

Summary: Monoclonal antibodies to IgE Description: Rat monoclonal anti-IgE antibodies that was generated by fusion of plasmacytoma (84.1C) or myeloma (EM953) cells with splenocytes of rat immunized with purified murine IgE mAb. The antibodies react with various IgE mAb of different specificities and not with immunoglobuli ... Read more

Diastereomer Lytic Peptides for Treatment of Solid Tumors and Metastasis in animal models (No. T4-236)

Scientist: Yechiel Shai

Summary: 236-237 - Diastereomer Lytic Peptides for Treatment of Solid Tumors and Metastasis Description: 15-mer (Leu-Lys-Dleu- Leu-Lys-Dlys-Leu-Dleu-Dlys-Lys-Leu-Leu-Dlys-Leu-Leu) and 15-mer Histidin (H-Leu-Lys-D-Leu- Leu-His-D-Lys-Leu-D-Leu-D-Lys-His-Leu-Leu-D-Lys-Leu-Leu-NH2) are membrane-active peptides composed of both ... Read more

15-mer Histidin (No. T4-237)

Scientist: Yechiel Shai

Summary: 236-237 - Diastereomer Lytic Peptides for Treatment of Solid Tumors and Metastasis Description: 15-mer (Leu-Lys-Dleu- Leu-Lys-Dlys-Leu-Dleu-Dlys-Lys-Leu-Leu-Dlys-Leu-Leu) and 15-mer Histidin (H-Leu-Lys-D-Leu- Leu-His-D-Lys-Leu-D-Leu-D-Lys-His-Leu-Leu-D-Lys-Leu-Leu-NH2) are membrane-active peptides composed of both ... Read more

Core peptide to inhibit T-Cell mediated inflammation in animal models (No. T4-238)

Scientist: Yechiel Shai

Summary: 238 - CP Peptide Description: Core peptide (CP; GLRILLLKV-D-stereoisomer), a synthetic peptide coding for the transmembrane domain of the ?-subunit of the T-cell receptor (TCR), a region that has been identified to be crucial for the assembly and function of the TCR. Was shown to significantly inhibit T-cell-media ... Read more

Anti-Mono-ubiquitinated H2B monoclonal antibody (No. T4-240)

Scientist: Moshe Oren

Summary: 240 - Monoclonal antibody directed to ubiquitinated-H2B Description: Monoclonal antibodies, specific to ubiquitinated-H2B in its ubiquitinated form but not in its unmodified state, or to ubiquitin un-conjugated to H2B. Monoubiquitylated-H2B takes part in almost every molecular process associated with chromatin bio ... Read more

Anti-progesterone-7 monoclonal antibody (No. T4-252)

Scientist: Fortune Kohen

Summary: Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. Anti-idiotypic antibody raised against anti-progesterone-7- BSA.KLH conjugate (clone 2H4). Available clon ... Read more

Alpha-Anti Progesterone (2E11) (No. T4-253)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for peptide and steroid hormones Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. Anti-idiotypic antibodies to anti-steroids: 252-253 ... Read more

Monoclonal Anti-Gliomedin Antibody (Mab#94) (No. T4-257)

Scientist: Elior Peles

Summary: 257 - Monoclonal antibody to Gliomedin Description: Monoclonal antibody to Gliomedin (MAb 94) raised against a synthetic peptide corresponding to amino acid residues 273–287 (CVIPNDDTLVGRA), present in the extra cellular region of Rat Gliomedin. Gliomedin, a glial ligand for neurofascin and NrCAM, is expressed ... Read more

Monoclonal Anti-Ermin Antibody (Mab#160) (No. T4-258)

Scientist: Elior Peles

Summary: 258 - Monoclonal antibody to Ermin Description: Monoclonal antibody to Ermin (MAb160) raised against purified GST–Ermin (residues 1–261). Ermin is a marker of myelinating oligodendroglia, localized to the outer cytoplasmic lip of the myelin sheath and the paranodal loops. It was suggested to play a role in cyt ... Read more

Monoclonal Anti-Caspr Antibody (Mab#275) (No. T4-259)

Scientist: Elior Peles

Summary: 259 - Monoclonal antibody to Caspr Description: Monoclonal antibody to Caspr (Mab275), raised against the extracellular domain of Caspr. Caspr is a contactin-associated protein, part of the neurexin family of proteins. It lies in the paranodal section of the myelin sheath and has a role in myelin sheath attachmen ... Read more

Anti- Glutamate receptor (GluR3B) monoclonal antibody (No. T4-261)

Summary: 261 - Monoclonal antibody to GluR3B Description: Mouse monoclonal antibody (IgG2a), raised against a synthetic peptide of the Glutamate receptor (GluR3B), corresponding to amino acids 383-395 (NEYERFVPFSDQQISNDSSSSENR) of Leishmania donovani GluR3B. May be used for diagnosis as well as drug development for "autoim ... Read more

Monoclonal Antibodies Specific to Cholesterol/Ceramide Mixture Clone (No. T4-263)

Scientist: Lia Addadi

Summary: Originally raised against an artificial monolayer of lipid mixtures in, and were shown to specifically label the above domains in different cell membranes. Reference:  Scheffer L, Futerman AH, Addadi L. 2007. Antibody labeling of cholesterol/ceramide ordered domains in cell membranes. Chembiochem 8(18):2286-94. ... Read more

499F (No. T4-265)

Scientist: Lia Addadi

Summary: Monoclonal antibodies specific to cholesterol/ceramide mixture Description: Monoclonal antibodies specific for cholesterol/ceramide-rich domains (clones 405F, 14F, 499F) and cholesterol micro-domains (clones 36A1, 5881) in cell membranes. Originally raised against an artificial monolayer of lipid mixtures in, and ... Read more

Anti- estrone-3- glucuronide monoclonal antibody (No. T4-273)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for peptide and steroid hormones Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. 273 - Anti-idiotypic antibody against estrone-3-gl ... Read more

Anti-Estradiol 15 (No. T4-274)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for peptide and steroid hormones Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.   §  127, 274, 141 – Monoclonal antibodies to ... Read more

Anti-Estrone-3-Glucuronide monoclonal antibody (No. T4-275)

Scientist: Fortune Kohen

Summary: Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. Monoclonal antibodies raised against estrone-3-glucuronide-BSA. Available clones: 8A3 (Rat, IgG2a), 155B3. ... Read more

Anti-Estrone-3-Glucuronide monoclonal antibody (clones: 155B3, 8A3) (No. T4-276)

Scientist: Fortune Kohen

Summary: Monoclonal antibodies for peptide and steroid hormones Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. 275-276 – Monoclonal antibodies to estrone-3-gluc ... Read more

Anti-Runx-3 monoclonal antibody (No. T4-306)

Scientist: Yoram Groner

Summary: Monoclonal antibody to Runx-3 Description: Monoclonal antibody to Runx-3 raised against the Runx3 peptide TPSTPSPRGSLSTTSHF. Available clones: 62, H8. Runx-3 (Runt-related transcription factor 3) is a transcription factor, and a master regulator of lineage specific gene expression in several important developmenta ... Read more

Chromogenic substrate for serum paraoxonase (PONs) activity (No. T4-315)

Scientist: Dan Tawfik

Summary: 315 - TBBL (5-thiobutyl butyrolactone) Description: TBBL (5-thiobutyl butyrolactone) is a chromogenic lipo-lactone substrate for Serum paraoxonases (PONs), used for sera tests of PONs activity, based on their lactonase activity.  The primary enzymatic reaction produces an unstable intermediate that rapidly collap ... Read more

Anti-Mast cell Function-associated Antigen (MAFA) monoclonal antibody (No. T4-320)

Scientist: Israel Pecht

Summary: 320 - Monoclonal antibody G63 Description: Monoclonal antibodies to MAFA (Mast cell Function-associated Antigen), originally raised against intact rat RBL-2H3 cells. MAFA is a type II membrane glycoprotein, which was shown to inhibit the secretory response to the type. Binding of G63 antibody to MAFA was shown to ... Read more

Escherichia coli UTL2 (No. T4-358)

Scientist: Eitan Bibi

Summary: Escherichia coli UTL2 Description: A "leaky" strain of E. coli, which is significantly more susceptible to cytotoxic agents. UTL2 holds a mutation in the galU gene causing an impaired outer membrane. Reference:  Bibi E. 1996. Functional expression of mouse Mdr1 in an outer membrane permeability mutant of Escheric ... Read more

MyRepair Blood Test to Identify People at High Risk for Lung Cancer (No. T4-1033)

Scientist: Zvi Livneh

Summary: A novel diagnostic test to identify individuals with increased risk of lung cancer. Lung cancer is the number one killer among cancers, with 160,000 deaths/year in the USA and 1.6 million/year worldwide. Early detection of lung cancer increases 5-year survival rate from 4% to 54%. Moreover, the National Lung Cance ... Read more

Alignment of Non-Overlapping Sequences (No. T4-1121)

Scientist: Michal Irani

Summary: A method for aligning video images according to sequence. The problem of image alignment has been extensively studied, and successful approaches have been developed for solving this problem. However, these approaches turn out as problematic when there is insufficient overlap between the two images to allow extract ... Read more

Acquisition of Multidimensional NMR Spectra in a Single Scan (No. T4-1151)

Scientist: Lucio Frydman

Summary: A method to significantly shorten acquisition times of high-quality MRI images. Multidimensional nuclear magnetic resonance (NMR) is used nowadays in many applications (e.g., discovery of new pharmaceutical drugs, characterization of new catalysts, and investigation of the structure and dynamics of proteins). One ... Read more

Monoclonal Antibodies for Monitoring Hormone and Drug Additives in Food Providing Animals (No. T4-1166)

Scientist: Fortune Kohen

Summary: A series of monoclonal antibodies for monitoring hormone and drug additives in animals grown for the food industry. These include mAbs for peptide hormones, steroid hormones, drugs, leukotrienes, isoflavones, and veterinary drugs. ApplicationsMonitoring hormone and drug additives in food providing anim ... Read more

A Precise Method for Edge Detection in Images (No. T4-1250)

Scientist: Ronen Basri

Summary: A robust method of identifying moving or changing objects in a video sequence groups each pixel with other adjacent pixels according to either motion or intensity values. Pixels are then repeatedly regrouped into clusters in a hierarchical manner. As these clusters are regrouped, the motion pattern is refined, unt ... Read more

Optical Cross-Sectioning Multiphoton Microscopy Without Scanning (No. T4-1266)

Scientist: Yaron Silberberg

Summary: Fast cross-sectioning using multiphoton microscope.  The conventionally used laser-scanning microscopy, confocal and multiphoton microscopy, although being capable of performing optical sectioning, requires a long image acquisition time, tens of milliseconds per section in current commercial systems, due to the s ... Read more

Cholesterol Antibodies (No. T4-1267)

Scientist: Lia Addadi

Summary: Description: Monoclonal antibodies specific for cholesterol/ceramide-rich domains (clones 405F, 14F, 499F) and cholesterol micro-domains (clones 36A1, 5881) in cell membranes. Originally raised against an artificial monolayer of lipid mixtures in, and were shown to specifically label the above domains in differen ... Read more

Mouse IgE and Anti-Mouse IgE Monoclonal Antibodies (No. T4-1270)

Scientist: Zelig Eshhar

Summary: Monoclonal antibodies to IgE Description: Rat monoclonal anti-IgE antibodies that was generated by fusion of plasmacytoma (84.1C) or myeloma (EM953) cells with splenocytes of rat immunized with purified murine IgE mAb. The antibodies react with various IgE mAb of different specificities and not with immunoglobuli ... Read more

On-Chip Synthesis of Biomolecules (No. T4-1369)

Summary: A simple, single-step biochip platform for synthesis of biomolecules. Biochip technology is used today in measuring passive probe-target interactions i.e. measurement of the abundance of specific biomolecules). This technology can now be extended to include complex and cascaded activities on the chip. The present ... Read more

High-Performance Electrochromic Devices (No. T4-1380)

Scientist: Milko van der Boom

Summary: High performance electrochromic materials that exhibit a practical combination of low-voltage operation and efficient color switching as well as long-term stability have been developed by the group of Prof.< size=2 face=Verdana> van der Boom. Electrochromic materials undergo reversible optical changes in res ... Read more

Detecting Irregularities (such as suspicious movements) in Visual Data (No. T4-1381)

Scientist: Michal Irani

Applications Detecting suspicious and/or salient behaviors in video Attention and saliency in images Detecting irregular tissue in medical images Automatic visual inspection for quality assurance (e.g., detecting defects in goods) Generating a video summary/synopsis Intelligent fast forward Non-visual data ... Read more

Monoclonal Anti-Ubiquitinated Histone H2B Antibody (No. T4-1397)

Scientist: Moshe Oren

Summary: A novel antibody which can be used, for the first time, to recognize ubiquitinated histone 2B. This technology is novel in its ability to recognize proteins and their destinations, and may serve in diagnostics and immunoprecipitation processes. ApplicationsPrimary applications in research. Use as a det ... Read more

Automatic Animation in Video and Still Images (No. T4-1423)

Scientist: Yosef Yomdin

Summary: Many currently marketed animation tools enable users to define objects and provide them with motion, yet none enable the fast and automatic, animation of a full body captured in a single still photo. A new technology developed by a group of researchers from the Weizmann Institute of Science, enables automatic tran ... Read more

CD84 - a Novel Regulator of B-CLL Survival (No. T4-1441)

Scientist: Idit Shachar

Summary: Chronic lymphocytic leukemia (CLL), a malignant disease characterized by the accumulation of B lymphocytes in the blood, lymphoid organs, and bone marrow, is the second most common type of leukemia in adults, accounting for about 7,000 new cases of leukemia each year. Presently, there is no cure for CLL, and the o ... Read more

Inhibition of Nuclear Entry of MAPK Cascade Proteins as a Novel Mechanism for Treating Cancer (No. T4-1446)

Scientist: Rony Seger

Summary: Peptide sequences for efficient inhibition of nuclear translocation of proteins. The ability to regulate cellular localization of a biological component is important for many functions such as gene therapy, protection from toxic chemicals, transport of anti-cancer agents, and possibly preventing nuclear translocat ... Read more

Protecting RFID Tags from Power Analysis (No. T4-1447)

Scientist: Adi Shamir

Summary: A cheap and effective solution for protecting RFID tags from power attacks. RFID tags are secure tags present in many applications (e.g. secure passports). They are poised to become the most far-reaching wireless technology since the cell phone, with worldwide revenues expected to reach $2.8 billion in 2009. RFID ... Read more

Changing an Image Size without Information Loss (No. T4-1461)

Scientist: Michal Irani

Summary: Bidirectional Similarity offers a new approach to summarization of visual data (images and video) based on optimization of well defined similarity measure. Common visual summarization methods (mainly scaling and cropping) suffer from significant deficiencies related to image quality and loss of important data. Man ... Read more

Highly Sensitive Nanoscale Scanning Magnetic and Thermal Sensor (No. T4-1481)

Scientist: Eli Zeldov

Summary: A new technology developed by a group of researchers from the Weizmann Institute is a nanoscale sensor-on-tip for local magnetic signals and thermal dissipation with state-of-the-art sensitivity and spatial resolution. In light of the rapidly developing scanning-probe based technologies including nanomagnetism, sp ... Read more

Conductive Inorganic Fullerenes and Nanotubes (No. T4-1482)

Scientist: Reshef Tenne

Summary: Modification of the electronic properties of layered-type semiconductors can be accomplished by doping/alloying of the semiconductor. In the present disclosure we show that doping of MoS2 and WS2 nanotubes/nanoparticles can be accomplished by doping with either Re (n-type) or Nb (p-type) foreign atoms. These nanop ... Read more

Production of Amines from Alcohol and Ammonia (No. T4-1507)

Scientist: David Milstein

Summary: Amines are widely used in the production of numerous products for multiple industries and their use is expected to increase. Global amines market is expected to reach over $14 billion by 2020, with an average annual growth of 3.5%. Primary amines are most useful in the larger markets of ethanolamines and fatty ami ... Read more

Antibody Combinations in Treating Cancer (No. T4-1518)

Scientist: Yosef Yarden

Summary: Improved immunotherapy for breast cancer. Monoclonal antibodies (mAbs) to ErbB-2/HER2 growth factor receptor, or to its sibling, the epidermal growth factor receptor (EGFR), prolong survival of cancer patients, especially when combined with cytotoxic therapies. However, low effectiveness of therapeutic mAbs and th ... Read more

Increasing Resolution of an Image (No. T4-1522)

Scientist: Michal Irani

Summary: A method for enhancing the spatial and or temporal resolution (if applicable) of an input signal such as images and videos.   Many imaging devices produce signals of unsatisfactory resolution (e.g. a photo from a cell-phone camera may have low spatial resolution or a video from a web camera may have both spatial ... Read more

Optical Conversion (No. T4-1529)

Scientist: Yaron Silberberg

Summary: We present an efficient and robust broadband crystal optical conversion device. Various applications of laser optics require tunable laser sources. Currently, most frequency conversion devices rely on a single non-linear crystal, which is either temperature or angle tuned to enhance efficiency. This results only i ... Read more

Boosted Conversion of Cellulosic Biomass into Sugars (No. T4-1536)

Scientist: Ed Bayer

Summary: Designer cellulosomes are synthetic multi-enzyme complexes that can degrade cellulosic biomass efficiently and economically. The goal of second generation biofuel production is to efficiently convert agricultural waste, algae and other cellulosic biomass into sugar monomers.  Cellulosic biomass pretreated (e.g. ... Read more

Antibodies Directed to ErbB Ligandsfor Treating Cancer (No. T4-1549)

Scientist: Yosef Yarden

Summary: A tailor-made strategy for cancer treatment. The ErbB family of tyrosine kinase receptors and their ligands play important roles in development and tissue remodeling throughout adulthood. ErbB proteins are involved in several types of human cancer. Clinical studies indicate that over-expression of one or more ErbB ... Read more

Green Catalytic Formation of Alcohols, Amines, Amides, Imines and Esters under Mild Conditions (No. T4-1551)

Scientist: David Milstein

Summary: A novel set of manganese, ruthenium and related borohydride complexes (Pincer-type) were developed as remarkably efficient and environmentally-benign catalysts for the synthesis of alcohols, amines, amides, imines and esters, which are the basic building blocks for the research, chemicals, pharmaceutical and agroc ... Read more

In Silico Designed Synthetic Carbon Fixation Pathways for Superior Biomass Generation (No. T4-1556)

Scientist: Ron Milo

Summary: Synthetic carbon fixation pathways can allow plants to produce more biomass using the same amount of energy from sunlight. Novel carbon fixation cycles discovered at The Weizmann Institute hold potential to greatly increase the capacity of organisms to convert atmospheric carbon into sugars. Modern agriculture fac ... Read more

Inorganic Fullerene Coating for Medical Devices (No. T4-1566)

Scientist: Reshef Tenne

Summary: Novel nanoparticle lubricants can significantly reduce friction of different dental devices and enable reduction of treatment times. Different dental applications suffer from excessive friction, which severely compromise their function. For orthodontic procedures, friction significantly reduces effectiveness and t ... Read more

Monitoring and Classifying Complex Social Interactions (No. T4-1571)

Scientist: Tali Kimchi

Summary: A novel social behavior monitoring system automatically tracks the precise location of each animal at excellent temporal resolution. This innovative technology provides simultaneous identification of complex social and individual behaviors via an integration of RFID and video surveillance. There is a rapidly growi ... Read more

A Novel Database to Reduce Unsuccessful Cloning in E. Coli by Detection of Toxic Genes (No. T4-1576)

Scientist: Rotem Sorek

Summary: Synthetic genes are commonly used in academic and industrial applications, however in many cases these said genes can be toxic when inserted into the ubiquitously used E. coli. This is problematic as time and money is wasted on attempts to generate genes that will not function in E. coli. The problem is exacerbate ... Read more

Desulfurization of Flue-Gasses (No. T4-1577)

Scientist: Igor Lubomirsky

Summary: A novel desulfurization system achieves removal of sulfur dioxide (SO2) from industrial exhaust streams at efficiencies that can greatly supersede technologies currently in use. The chemical process is highly selective to SO2, and consumes much less reagents, therefore reducing the cost of desulfurization.Techniqu ... Read more

A Novel Technique of Thermoelectric Conversion (No. T4-1583)

Scientist: Yoseph Imry

Summary: The thermoelectric effect is the direct conversion of temperature differences to electric voltage and vice versa. Thermoelectric effects are used in various applications, where heat energy is saved, that would be otherwise lost. Although the TE conversion efficiency is nowadays low (5-8%), the novel technique deve ... Read more

Hip Replacment Monitoring Based on Audio Signal Processing (No. T4-1585)

Scientist: David Tannor

Summary: Our scientific team has discovered a method to apply the Gabor Transform to signal processing and data compression.Compared to existing methods that are based on Fourier transform, the new method provides for up to 25% savings in content size for video, audio and images, without any loss in quality.By embracing ou ... Read more

Extended Shelf-Life of Crop Plants by Reduction of Steroidal Glycoalkaloids Production (No. T4-1587)

Scientist: Asaph Aharoni

Summary: Different agricultural crops from Solanaceous species which include tomato, potato and eggplant, overcome oxidative stress by the production of steroidal glycoalkaloids (SGAs) and steroidal saponins. Although SGAs contribute to plant resistance to a wide range of pathogens and predators some are considered as toxi ... Read more

Novel MRI Contrast Agent (No. T4-1604)

Scientist: Michal Neeman

Summary: Novel reporter gene for magnetic resonance imaging applications.The ability to image the duration and location of gene expression in vivo and noninvasively is imperative for the future of biology and clinical medicine. Magnetic Resonance Imaging (MRI) is a widely used noninvasive clinical diagnostic tool that offe ... Read more

SiRNA Proteasome Inhibitors for Cancer Theraphy (No. T4-1619)

Scientist: Yosef Shaul

Summary: Triple negative breast cancer (TNBC) is an aggressive type of breast cancer, representing over 10% of all breast cancer cases. TNBC is known for its high risk of relapse, poor survival prospects, and near zero survival rates once TNBC metastasizes. Due to the lack of molecular targets (estrogen, progesterone, and ... Read more

A TACE Inhibitor (ADAM17) (No. T4-1628)

Scientist: Irit Sagi

Summary: New generation of superior nature-inspired therapeutics for treating inflammation.Inflammation is characterized by elevated levels of TNF-?. Neutralizing TNF-? activity was shown to be beneficial for patients with chronic autoimmune inflammatory diseases such as rheumatoid arthritis (RA) and inflammatory bowel dis ... Read more

Novel Aptamer for Cancer Therapy (No. T4-1633)

Scientist: Yosef Yarden

Summary: The ErbB family consists of four structurally related receptor tyrosine kinases. Excessive ErbB signaling is associated with enhanced tumorogenesis, and as such serves as a major therapeutic target in a wide array of solid tumor cancers. A member of this family, the human epidermal growth factor receptor 2 (ErbB-2 ... Read more

Biological Treatment for Pancreatic Cancer (MMP7 mAb) (No. T4-1640)

Scientist: Irit Sagi

Summary: The innovative concept leading to this high selectivity is immunization with both a synthetic metal-protein mimicry molecule, previously developed by the present inventors, followed by the metalloenzyme itself (e.g. MMP-7). The resulting antibody exhibits exceptional degree of specificity towards MMP-7 over other ... Read more

Anti-QSOX1 Antibody for Treating Cancer and Metastasis (No. T4-1642)

Scientist: Deborah Fass

Summary: A potential target for anticancer drug design.Cancer is the second leading cause of death in the US, accounting for roughly 23% of all deaths (as of 2008), and with estimated cost of care of $157 billion (as of 2010). Despite major advances in the management of cancer, most types of solid tumors remain resistant t ... Read more

Unsupervised Content-Based Image Retrieval (CBIR) and categorization (No. T4-1647)

Scientist: Michal Irani

Summary: Novel algorithms developed at the Weizmann Institute of Science for Content-Based Image Retrieval (CBIR) can enhance search engines by crowd-sourcing and improved clustering.Discovering visual categories among collection of images is a long standing challenge in computer vision, which limits images-based search en ... Read more

Affinity Maturated T-Cell Receptor (No. T4-1662)

Scientist: Lea Eisenbach

Summary: Immunotherapy, that is the use of the immune system to treat cancer, is currently a leading candidate in the combat against cancer. Unlike the toxic effects of both chemotherapy and radiation, immunotherapy is considered to have mild side effects due to its ability to differentiate between healthy and cancerous ce ... Read more

MRI of Tissue Fibrosis Without Contrast Agent (No. T4-1665)

Scientist: Michal Neeman

Summary: Improved magnetic resonance imaging (MRI) for cardiac fibrosis and other fibrotic diseases.Myocardial fibrosis is associated with worsening ventricular systolic function, abnormal cardiac remodeling, and increased ventricular stiffness, significantly increasing the risk of adverse cardiac outcomes. Hypertension an ... Read more

Mutant P53 Reactivating Peptides as a Novel Cancer Therapy (No. T4-1672)

Scientist: Varda Rotter

Summary: Newly developed p53-reactivating peptides were shown to cause regression of very aggressive tumors in several cancer models. p53 is the most important  tumor suppressor gene. Mutant p53 forms can instigate a cascade of events that may lead to loss of control of cell growth and proliferation, and eventually to can ... Read more

Long Chain Sphingoid as Preventing Infection (No. T4-1673)

Scientist: Anthony H. Futerman

Summary: CF is the most common autosomal recessive disorder in western countries, affecting approximately 30,000 people in the US alone. A major risk in CF arises from chronic bacterial lung infections, affecting 80% of CF patients by the age of 25. Bacterial lung infections are also of major clinical importance in patient ... Read more

Highly Selective Optical Biosensors for Proteins in Biological Samples, with Excellent Signal-to-Noise Ratio (No. T4-1689)

Scientist: David Margulies

Summary: Sensing the levels of protein-based biomarkers in biological samples is crucial for diagnosis of various diseases including cancer. Optical biosensors offer sensitivity and cost-effectiveness; however, current commercially available devices fail to provide sufficient selectivity and signal to noise ratios for prot ... Read more

Production of Syngas from Biomass (No. T4-1716)

Scientist: Ronny Neumann

Summary: An efficient and selective decomposition of plant biomass carbohydrates to their basic components, carbon monoxide and hydrogen, for use as syngas.Terrestrial plants contain about 70% hemicellulose and cellulose, which constitute a significant renewable bio-resource with potential as an alternative to petroleum fe ... Read more

Photon Up Conversion Nanocrystals (No. T4-1717)

Scientist: Dan Oron

Summary: Currently available systems, based on rare-earth-doped dielectrics, and organic materials are limited in both tunability and absorption cross-section. In fact, no known up-conversion systems operate on photons in the 1000-1500 nm range. Stable inorganic nanocrystalline up-conversion systems designed at the Weizman ... Read more

Aerobic Carbon-Carbon Bond Cleavage of Alkenes to Aldehydes and Ketones (No. T4-1722)

Scientist: Ronny Neumann

Summary: Our technology provides a new type of oxidative cleavage reaction of organic compounds with highly selective product formation.Polyoxometalate (POM) catalysts have become well-known for their utility and diversity in specific reactions. Through the elucidation of POM catalytic pathways, greater versatility has bee ... Read more

Biocontrol Enhancers to Promote Root Colonization by Beneficial Bacteria (No. T4-1723)

Scientist: Ilana Kolodkin-Gal

Summary: Available chemically based pesticides cause a large number of negative health and environmental effects including the outcome of residual contamination of land, water, and crops. Subsequently there is a need for improved methods of crop protection, preferably the use of environmental friendly alternatives of biolo ... Read more

Carbon Nanotube Based Transistor Device (No. T4-1730)

Scientist: Shahal Ilani

Summary: With the continuous trend of electronic component miniaturization, process control technologies must keep up with component size reduction. Defects that were so far negligible, are now posing critical operation obstacles, and are more difficult to identify as scales are reduced to <10 nm. This new technology de ... Read more

P38 and JNK Inhibitor as Potential Treatment for Various Pathologies (No. T4-1733)

Scientist: Rony Seger

Summary: Recently, Prof. Zeger and his team discovered a new level of regulation to stimulated transcription. They showed that ?-like importunes are central mediators of nuclear translocation of signaling proteins. Furthermore they identified the site of interaction and designed accordingly a peptide which was found to pre ... Read more

Bioengineered Microorganisms that can "Eat" (Fix) CO2 (No. T4-1736)

Scientist: Ron Milo

Summary: Biomass production by plants and other photosynthetic organisms involves carbon fixation, the process of incorporating inorganic carbon dioxide into organic compounds. Currently carbon fixation by plants and other photosynthetic organisms is the limiting factor in biomass production. Improvement in the metabolic p ... Read more

A Novel Approach for Treating Cancer and Collagen-Associated Diseases by Using Anti-LOXL-2 Antibody (No. T4-1743)

Scientist: Irit Sagi

Summary: Disruption to the Extra-Cellular Matrix (ECM) is associated with many pathological conditions, such as various cancer types and tissue fibrosis, and also correlates with high tumor malignancy. Therefore, controlling ECM composition and morphology is considered a potential treatment for cancer and other ECM-associa ... Read more

Catalytic Liquid Organic Hydrogen Carrier (LOHC) System (No. T4-1749)

Scientist: David Milstein

Summary: A novel Liquid Organic Hydrogen Carrier (LOHC) system provides an inexpensive, safe and clean solution for loading and unloading of hydrogen on demand with high potential hydrogen storage capacity.The thriving need for fossil fuels alternatives as energy resources in order to maintain the fast development of human ... Read more

rPTE with Potent Organophosphate (OPH) Activities (No. T4-1750)

Scientist: Dan Tawfik

Summary: Organophosphates are toxic compounds found in chemical warfare agents, such as nerve gases, and insect pesticides.Use of volatile nerve gas agents by terrorist organizations is a key concern of governments around the world. V-type nerve agents (e.g. VX, RVX, and CVX) are particularly toxic nerve gases, with an exc ... Read more

ERBB2 as a Novel Target to Treat Heart Failure by Inducing Cardiomyocyte Proliferation (No. T4-1752)

Scientist: Eldad Tzahor

Summary: Existing treatments fail to compensate the irreversible loss of functional cardiomyocytes (CM), thus presenting a major medical unmet need. Inducing native CM replacement is one approach being tested as regenerative treatment, with the advantage of a more straightforward methodology over cell transplantation appro ... Read more

Spin Controlled Water Electrolysis for Efficient Production of Hydrogen (No. T4-1753)

Scientist: Ron Naaman

Summary: A team of researchers lead by Prof. Naaman have been investigating the CISS effect in different systems. They found that the high efficiency of many natural multiple electron reactions can also be attributed to spin alignment of the electrons involved.The present innovation looks at hydrogen production through wat ... Read more

Multimodel Transcranial Optical Vascular Assessment (No. T4-1769)

Scientist: Alon Harmelin

Summary:         Subdural hematoma (SDH) is a collection of blood between the inner layer of the dura and the brain that occurs mostly as a result of trauma.  It is one of the most common neurosurgical conditions in the United States today. SDH monitoring for hematoma expansion would be beneficial to enable expeditiou ... Read more

A Novel Method for Treating Drug-Resistant Lung Cancer Using a Combination of Antibodies (No. T4-1774)

Scientist: Yosef Yarden

Summary: A novel method for treating tyrosine kinase inhibitor (TKI)-resistant cancer, by using a combination of three different antibodies. Lung cancer is known as one of the most fatal forms of cancer. Notably, standard treatments for other cancer types (e.g. TKIs and mAbs), have shown only a limited effect on this speci ... Read more

A Novel Method of Treating Cancer by Targeting EGFR Ligand Amphiregulin (No. T4-1776)

Scientist: Yosef Yarden

Summary: A novel method for treating ovarian cancer by intercepting the EGFR ligand amphiregulin, when elevated expression levels are found in a patient. Ovarian cancer represents a relatively common type of cancer that affects women. However, the primary therapeutic option for ovarian cancer has remained the same since th ... Read more

Process for the Preparation of Halide Perovskite Andperovskite-Related Materials (No. T4-1786)

Scientist: David Cahen

Summary: Perovskites are a class of crystalline materials that have in general a chemical formula of ABX3. Lead-halide hybrid organic-inorganic perovskites have recently emerged as highly efficient optoelectronic materials. Such materials are being intensively investigated and developed for photovoltaics (PV), photo detect ... Read more

A Novel Method of Preventing or Treating Secondary Infections by Inhibition of Membrane Type I Matrix-Metalloproteinase-1 (No. T4-1790)

Scientist: Irit Sagi

Summary: A novel method of preventing secondary infections, by inhibition of membrane type I matrix-metalloproteinase-1 (MT1-MMP), which reduces degradation of the extra-cellular matrix. Pathogens that infect the respiratory system are the cause of some of the most dangerous infections, especially for vulnerable population ... Read more

Removing Artifacts from EEG Measurments Triggerd by Transcranial Magnetic Stimulation (No. T4-1800)

Scientist: Elisha Moses

Summary: A new software tool used for the removal of artifacts from transcranial magnetic stimulation (TMS) triggered electroencephalography (EEG) was developed by the group of Prof. Moses. The combined use of TMS with EEG allows for a unique measurement of the brain's global response to localized and abrupt stimulations. ... Read more

A Sensitive and Fast Image Subtrection Technique (No. T4-1801)

Scientist: Avishay Gal-Yam

Summary: Image sequences are used in various fields, including medical imaging and satellite/airborne imaging. The comparison between images taken at different conditions (e.g. equipment or configuration, angles, weather and wavelength) can be a highly non-trivial problem, as subtraction artifacts can outnumber real change ... Read more

Detection of Short Dispered Pulse Signals (No. T4-1802)

Scientist: Avishay Gal-Yam

Summary: Pulses are applied in various fields such as oil & gas exploration, detection (e.g. sonar, lidar and radar) and communication. When pulses pass through dispersive media, the arrival times at the detector of different frequency components may differ, and as a result the pulse may become degraded (e.g. transform ... Read more

Novel Method for Diagnosing and Treating Relapsed Obesity (No. T4-1805)

Scientist: Eran Segal

Summary: Obesity is the health epidemic of the modern world, with nearly half the global adult population being categorized as obese. The consequences of said mass obesity is that it is overwhelming the medical systems all over the world, as obesity is linked to numerous diseases ranging from diabetes to cancer. The challe ... Read more

Novel CNT Hybrid Films Used as Porous Electrodes (No. T4-1809)

Scientist: Boris Rybtchinski

Summary: Battery and capacitor electrode technologies available in the industry today, are struggling to keep up with rapidly advancing applications that require high power and energy density such as electric vehicles, solar cells and telecommunications systems. One of the leading solutions to this problem are CNT-based fi ... Read more

A Novel Technique to Produce Large Quantities of Therapeutic T cells (No. T4-1810)

Scientist: Benjamin Geiger

Summary: Culturing and expanding T cells ex-vivo, while retaining their functionality, is an essential factor for the development of cutting-edge immunotherapies. A major problem frequently faced by physicians is the low number of T cells available for adoptive immunotherapy, and the difficulty to retain their functionalit ... Read more

Increasing Plant Yield by Inhibiting Attenuating Enzymes (No. T4-1812)

Scientist: Avihai Danon

Summary: A growing global population requires a greater food supply. The agriculture industry and biotechnology sector are trying to overcome the challenge and improve crop efficiency by increasing food production in the same or smaller farming areas, as well as dealing with the threats imposed by climate change. Consequen ... Read more

Devices and Methods to Measure Small Displacements (No. T4-1815)

Scientist: Igor Lubomirsky

Summary: This novel method utilizes polarized light that in contrast to conventional methods does not interact directly with the material or with the material’s surface. Here the material to be tested is secured underneath a reflective material, such that the polarized light reflected off the reflective material does not ... Read more

Inertial NEMS for Nanosensor Applications Based on Inorganic Nanotubes (No. T4-1828)

Scientist: Ernesto Joselevich

Summary: Inertial sensors for motion detection are being incorporated into an increasing number of portable devices, including diverse IoT applications, mobile phones, wearable electronics, automotive systems and medical diagnostic sensors. The current size reduction trend in electronics, requires incorporation of reliable ... Read more

Highly Selective Fluorescent Biosensor for Labeling His-Tagged Proteins in a Specific Conformation (No. T4-1834)

Scientist: David Margulies

Summary: A rapid, label-free biosensor for detecting specific conformation of His-tag labeled proteins, accessible for use in both academic- and commercial-R&D. The fluorescent biosensor detects and labels His-tagged proteins in complex environments, such as living cells, while offering high sensitivity, speed, and cos ... Read more

A Novel Method for Detecting Activation of Necroptosis via Exosome Analysis (No. T4-1839)

Scientist: David Wallach

Summary: Numerous medical conditions are related to inflammation, such as pancreatitis, psoriasis, inflammatory bowel disease, atherosclerosis, neurodegeneration, and more. However, determination of inflammation in the body, especially at early stages of a pathology is difficult to assess. Therefore, there is a great clini ... Read more

Secure Search of Encrypted Cloud Data (No. T4-1840)

Scientist: Moni Naor

Summary: Searchable symmetric encryption with practical big-data performance and strong security Highlights Outsourcing data storage to remote servers offers invaluable benefits while introducing many concerns when dealing with sensitive data. In the presence of potentially-vulnerable servers, strong user-side encryption p ... Read more

Methods for High-Throughput Analysis of Transcriptomes (No. T4-1843)

Scientist: Ido Amit

Summary: Analysis of the transcriptome of cells can inform greatly about the state of said cells, including maturation, activation, transformation, etc. Therefore it would be of great research and clinical value to analyze transcriptomes of different cell populations and to compare gene expression on large scales. A partic ... Read more

Composite Functional Metasurfaces for Multispectral Achromatic Optics (No. T4-1845)

Scientist: Yehiam Prior

Summary: A new technology for producing flat optical components based on optical metasurfaces. These components can potentially serve high resolution imaging, spectrometry, light processing and beam shaping devices. The optical metasurfaces that we develop are composed of closely spaced optical nanoantennas which can be ... Read more

Improving Efficiency of CRISPR Genome Editing in Plants (No. T4-1846)

Scientist: Asaph Aharoni

Summary: CRISPR/Cas9 represents a revolutionary jump in genome editing technology, both in terms of flexibility and accuracy. However, an acute challenge for the use of CRISPR/Cas9 in editing plant genomes is that the system has a low efficiency in producing the desired modifications. Therefore, there is a clear need for a ... Read more

A Novel Approach for Controlling Gene Expression (Arbirtium - a Novel approach) (No. T4-1847)

Scientist: Rotem Sorek

Summary: One of the challenges in the areas of synthetic biology and its clinical applications, is the capacity to control the induction of different genes, whether for the purpose of activating genetic circuits or inducing the expression of a specific protein. Present approaches are limited to the number of systems availa ... Read more

CRISP-Seq: Integrating the Power of Single-Cell RNA Sequencing and CRISPR-Pooled Screens (No. T4-1848)

Scientist: Ido Amit

Summary: Single-cell RNA sequencing (RNA-Seq) is a powerful tool to identify and characterize the transcriptome of single cells. While providing unprecedented resolution in terms of studying cells, single-cell RNA-Seq is functionally a descriptive tool, unless combined with gene manipulation. CRISPR-Cas9 is a genome-editin ... Read more

Signal Enhancement and Manipulation Using a Signal-Specific Deep Network (No. T4-1850)

Scientist: Michal Irani

Summary: Optical and dimensional limitations of images can be partially overcome today using signal enhancement technologies which typically rely on supervised, deep-learning methods. However, as existing methods are restricted to specific training images and distortion types, they provide poor results for any practical ca ... Read more

Optical Bus for a Multi-Core Processor (No. T4-1863)

Scientist: Ulf Leonhardt

Summary: The exponential increase in computational power over the last decades is running into a bottle-neck – the only way of getting more computing power per chip is to integrate multiple-cores, but the problem with multiple-cores is the complex wiring system, used for inter-core communication. This technology, develop ... Read more

Novel Treatment for Lung Diseases by Allogeneic Cell Transplantation (No. T4-1868)

Scientist: Yair Reisner

Summary: The treatment of respiratory conditions is currently one of the major challenges to health care systems all over the world. The problem is that most therapeutics currently available for treating pulmonary indications are non-curative, and simply improve symptoms. Presently the only cure for late stage pulmonary di ... Read more

Targeted Exchange Between Homologous Chromosomes - A New Tool for Precise Breeding (No. T4-1871)

Scientist: Avraham Levy

Summary: As the world’s population grows, and climate changes, there is a strong need for breeding hardier crops in a precise fashion. The traditional method of introducing new traits to a plant via traditional breeding methods is a slow and stochastic process, which can require growing a large number of plants to screen ... Read more

Novel Method for Diagnosis and Treating Cancer by Analyzing the Urea Cycle (No. T4-1872)

Scientist: Ayelet Erez

Summary: The urea cycle (UC) is an important metabolic pathway that takes place in the liver. A variety of enzymes, such as argininosuccinate synthase 1 (ASS1) and the trifunctional enzyme CAD, are involved in the UC, which converts excess nitrogen into urea. The UC produces various metabolites based on the balance between ... Read more

A Method in Improving Survival and Expansion of Hematopoietic Stem Cells (No. T4-1874)

Scientist: Idit Shachar

Summary: hematopoietic cells. HSCs have the capacity to both self-renew and to differentiate, and they migrate from the bone marrow to the blood upon demand. Since HSCs can differentiate to a variety of cell types, including immune system cells, they have a huge therapeutic potential. Indeed, bone marrow transplantation is ... Read more

Inhibiting Importin to Treat Psychiatric Stress and Other Disorders (No. T4-1875)

Scientist: Michael Fainzilber

Summary: Anxiety and stress-related disorders effect 10-30% of the general population and are therefore considered a major burden on public health. Current medical treatments for anxiety disorders include drugs that target various synaptic mechanisms, such as uptake of neurotransmitters. However, severe side-effects and su ... Read more

Universal CAR-Ts (No. T4-1884)

Scientist: Zelig Eshhar

Summary: Chimeric Antigen Receptor T-Cells (CAR-Ts) are one of the revolutionary technologies of the twenty-first century, invented by Prof. Zelig Eshhar at the Weizmann Institute of Science. The CAR-T technology represents a leap in terms of treating cancer, as the technology programs an individual’s immune system to sp ... Read more

Device for Electric Field Induced Local Magnetization (No. T4-1886)

Scientist: Ron Naaman

Summary: A new technology developed by a group of researchers led by Prof. Ron Naaman from the Weizmann Institute, harnesses the advantages of electron spin orientation for memory and information transmission applications. The innovation enables replacement of the traditional current-based semiconductor technologies, yield ... Read more

A New Sustainable Process for Hydrocarbons Oxidation (No. T4-1892)

Scientist: Ronny Neumann

Summary: Phenol is an important industrial commodity used as a precursor to many useful compounds. It is being utilized in huge amounts in a wide range of industry sectors including the pharmaceuticals, plastic-related-products production, paints & coatings, electrical equipment, foams and fuel additives. The global ph ... Read more

Disrupting or Preventing Formation of Biofilm by Enzyme Inhibitors (No. T4-1893)

Scientist: Ilana Kolodkin-Gal

Summary: Biofilm is a complex colony of bacteria, which are attached together by extracellular polymeric substance. This setting provides the bacteria protection against environmental factors, improves their surface attachment, and plays a major role in resistance to treatment. Therefore, biofilms are difficult to eradicat ... Read more

Person-specific Assessment of Probiotics Responsiveness (No. T4-1895)

Scientist: Eran Segal

Summary: Dietary supplementation with commensal microorganisms, collectively termed probiotics, is a constantly growing market, estimated to exceed 69.3 billion USD by 2023. Probiotics are the third most commonly consumed dietary supplement after vitamin and mineral preparations. Claimed rationales for probiotics consumpti ... Read more

WS2 NANOTUBE-REINFORCED BIODEGRADABLE AND BIOCOMPATIBLE POLYMER INK FOR 3D PRINTING (No. T4-1900)

Scientist: Reshef Tenne

Summary: Biocompatible polymers commonly used in the orthopedic and cosmetic prosthetics, cardiovascular and dental implants and food packaging industries often suffer from poor mechanical properties and thermal stability, limited dimensionality and short shelf-life as compared to their metal comparators. Two research grou ... Read more

Photovoltaic Devices Based on Guided Nanowire Arrays (No. T4-1906)

Scientist: Ernesto Joselevich

Summary: Nanowires are being produced and integrated into various systems today, including solar cells, nano-sensors, nano-electrodes, transparent touch-screen coatings, and LED replacements. Thus far, several challenges have hindered the commercial advancement of nanowire-based technologies. Two major setbacks have been: ... Read more

Extraction of Gold from Electronic Waste and Ores (No. T4-1910)

Scientist: Igor Lubomirsky

Summary: A method for selective extraction of gold has been developed at the Weizmann Institute. This method allows the efficient and environmentally benign recovery of gold that is currently discarded of in large quantities from electronic waste from household appliances, consumer electronic devices and industrial equipme ... Read more

Methods of Identifying and Using Agents for Treating Diseases Associated with Intestinal Barrier Dysfunction (No. T4-1925)

Scientist: Benjamin Geiger

Summary: The obesity pandemic has reached alarming magnitudes, affecting more than 2 billion people worldwide and accounting for more than 3 million deaths per year. A poorly understood feature of the ‘metabolic syndrome’ is its association with dysfunctions of the intestinal barrier, leading to enhanced permeability a ... Read more

Molecular Switches in Solid Media (No. T4-1927)

Scientist: Rafal Klajn

Summary: Molecular photoswitches are light-responsive molecules with potential applications in a broad range of systems with on-demand functionalities. While molecular photoswitches have been extensively studied in solution, their immobilization to dry, planar surfaces generally renders them photochemically unresponsive. T ... Read more

Artificial Pancreas (No. T4-1942)

Scientist: Eran Segal

Summary: The alarmingly sharp increase in type 1 diabetes mellitus incidence in recent years has been coupled with a marked rise in the development of closed-loop systems aimed at continuously monitoring blood glucose levels, predicting glucose behavior and delivering adjusted insulin doses. However, to date, these systems ... Read more

Bacterial Anti-Phage Defense Systems (No. T4-1690)

Scientist: Rotem Sorek

Cell Surface Modification with Synthetic Receptors (No. T4-1961)

Scientist: David MARGULIES

Continuous Monitoring of Algae Crops Using Minimum Optical Information (No. T4-1908)

Scientist: Yinon Rudich

Agrin – A Novel Protein-Based Therapeutic Agent for Heart Diseases (No. T4-1787)

Scientist: Eldad Tzahor

Background and Unmet NeedHeart disease is the number one cause of death, surpassing the number of deaths from all cancers combined. Its burden on society and healthcare systems is immense. The inspiring studies from one of the top leaders in the field of cardiac regeneration, Prof. Eldad Tzahor of the Weizmann Institute ... Read more

Small molecule as a potential treatment for Glaucoma (No. T4-1433)

Scientist: Steven J.D. Karlish

A Blood Glutamate Scavenger for the Treatment of Acute Neurodegenerative Disorders (No. T4-1153)

Scientist: Vivian I. Teichberg