Regulating ErbB2 signaling in cardiomyocytes (CM) as novel treatment for heart diseases by inducing regeneration of cardiac tissue. ... Read more

Sphingosine (SPH), a natural bactericidal agent which acts as a part of the human innate immune system in the skin, was found to be an effective treatment and prophylaxis for bacterial lung infections in cystic fibrosis (CF) mice. ... Read more

Cardiac fibrosis is a scarring event in the cardiac muscle that causes abnormalities in cardiac function and significantly increases the risk of sudden cardiac death. ... Read more

Using affinity maturated TCRs to generate reactive T cells ... Read more

Cancer, and especially cancer metastasis, is a leading cause of death worldwide. Research in recent years highlighted the importance of the extracellular matrix (ECM) surrounding the tumor in cancer progression metastasis formation. ... Read more

A novel therapeutic antibody against MMP-7, with exceptional specificity, for the treatment of aggressive cancers. ... Read more

Glaucoma is one of the leading causes of irreversible blindness worldwide, affecting over 60 million people. It is usually caused due to raised intraocular pressure (IOP). ... Read more

Cell-free synthetic platforms that enable complex biological activities such as synthesis and self-assembly of biomolecules, can be employed for various applications, including drug discovery and diagnostics. ... Read more

Description: Monoclonal antibodies specific for cholesterol/ceramide-rich domains (clones 405F, 14F, 499F) and cholesterol micro-domains (clones 36A1, 5881) in cell membranes. Originally raised against an artificial monolayer of lipid mixtures in, and were shown to specifically label the above do ... Read more

A novel diagnostic test to identify individuals with increased risk of lung cancer ... Read more