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  • A Novel Approach for Controlling Gene Expression (Arbirtium - a Novel approach) (No. 1847)

    Scientist: Rotem Sorek

    One of the challenges in the areas of synthetic biology and its clinical applications, is the capacity to control the induction of different genes, whether for the purpose of activating genetic circuits or inducing the expression of a specific protein. Present approaches are limited to the number of systems available, in ... Read more
    5695
  • Cholesterol Antibodies (No. 1267)

    Scientist: Lia Addadi

    Description: Monoclonal antibodies specific for cholesterol/ceramide-rich domains (clones 405F, 14F, 499F) and cholesterol micro-domains (clones 36A1, 5881) in cell membranes. Originally raised against an artificial monolayer of lipid mixtures in, and were shown to specifically label the above domains in different cell ... Read more
    5449
  • Fully Naive Induced Human Pluripotent Stem Cells (iPSC) (No. 1671)

    Scientist: Jacob (Yaqub) Hanna

    A novel method to revert human iPSC to a fully naive state, retaining stable pluripotency. The feasibility for the existence of ground state naive pluripotency in human embryonic stem cells (hESC) has long been researched. This innovative technology supplies the composition of chemically defined conditions required for d ... Read more
    5578
  • Novel Treatment for Lung Diseases by Allogeneic Cell Transplantation (No. 1868)

    Scientist: Yair Reisner

    The treatment of respiratory conditions is currently one of the major challenges to health care systems all over the world. The problem is that most therapeutics currently available for treating pulmonary indications are non-curative, and simply improve symptoms. Presently the only cure for late stage pulmonary diseases ... Read more
    5707
  • Mouse IgE and Anti-Mouse IgE Monoclonal Antibodies (No. 1270)

    Scientist: Zelig Eshhar

    Monoclonal antibodies to IgE Description: Rat monoclonal anti-IgE antibodies that was generated by fusion of plasmacytoma (84.1C) or myeloma (EM953) cells with splenocytes of rat immunized with purified murine IgE mAb. The antibodies react with various IgE mAb of different specificities and not with immunoglobulins of o ... Read more
    5452
  • Mutant P53 reactivating peptides as a novel cancer therapy (No. 1672)

    Scientist: Varda Rotter

    Newly developed p53-reactivating peptides were shown to cause regression of very aggressive tumors in several cancer models. p53 is the most important  tumor suppressor gene. Mutant p53 forms can instigate a cascade of events that may lead to loss of control of cell growth and proliferation, and eventually to cancer. p5 ... Read more
    5581
  • Novel Method for Diagnosis and Treating Cancer by Analyzing the Urea Cycle (No. 1872)

    Scientist: Ayelet Erez

    The urea cycle (UC) is an important metabolic pathway that takes place in the liver. A variety of enzymes, such as argininosuccinate synthase 1 (ASS1) and the trifunctional enzyme CAD, are involved in the UC, which converts excess nitrogen into urea. The UC produces various metabolites based on the balance between its co ... Read more
    5713
  • On-Chip Synthesis of Biomolecules (No. 1369)

    A simple, single-step biochip platform for synthesis of biomolecules. Biochip technology is used today in measuring passive probe-target interactions i.e. measurement of the abundance of specific biomolecules). This technology can now be extended to include complex and cascaded activities on the chip. The present immobil ... Read more
    5455
  • Long chain sphingoid as preventing infection (No. 1673)

    Scientist: Anthony H. Futerman

    CF is the most common autosomal recessive disorder in western countries, affecting approximately 30,000 people in the US alone. A major risk in CF arises from chronic bacterial lung infections, affecting 80% of CF patients by the age of 25. Bacterial lung infections are also of major clinical importance in patients with ... Read more
    5584
  • A Method in Improving Survival and Expansion of Hematopoietic Stem Cells (No. 1874)

    Scientist: Idit Shachar

    hematopoietic cells. HSCs have the capacity to both self-renew and to differentiate, and they migrate from the bone marrow to the blood upon demand. Since HSCs can differentiate to a variety of cell types, including immune system cells, they have a huge therapeutic potential. Indeed, bone marrow transplantation is a comm ... Read more
    5716

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