Scientist: Yosef Yarden

The ErbB family consists of four structurally related receptor tyrosine kinases. Excessive ErbB signaling is associated with enhanced tumorogenesis, and as such serves as a major therapeutic target in a wide array of solid tumor cancers. A member of this family, the human epidermal growth factor receptor 2 (ErbB-2/HER2), ... Read more

Scientist: Eran Segal

Obesity is the health epidemic of the modern world, with nearly half the global adult population being categorized as obese. The consequences of said mass obesity is that it is overwhelming the medical systems all over the world, as obesity is linked to numerous diseases ranging from diabetes to cancer. The challenge is ... Read more

Scientist: Ayelet Erez

The urea cycle (UC) is an important metabolic pathway that takes place in the liver. A variety of enzymes, such as argininosuccinate synthase 1 (ASS1) and the trifunctional enzyme CAD, are involved in the UC, which converts excess nitrogen into urea. The UC produces various metabolites based on the balance between its co ... Read more

Scientist: Yair Reisner

The treatment of respiratory conditions is currently one of the major challenges to health care systems all over the world. The problem is that most therapeutics currently available for treating pulmonary indications are non-curative, and simply improve symptoms. Presently the only cure for late stage pulmonary diseases ... Read more

A simple, single-step biochip platform for synthesis of biomolecules. Biochip technology is used today in measuring passive probe-target interactions i.e. measurement of the abundance of specific biomolecules). This technology can now be extended to include complex and cascaded activities on the chip. The present immobil ... Read more

Scientist: Rony Seger

Recently, Prof. Zeger and his team discovered a new level of regulation to stimulated transcription. They showed that ?-like importunes are central mediators of nuclear translocation of signaling proteins. Furthermore they identified the site of interaction and designed accordingly a peptide which was found to prevent nu ... Read more

Scientist: Eran Segal

Dietary supplementation with commensal microorganisms, collectively termed probiotics, is a constantly growing market, estimated to exceed 69.3 billion USD by 2023. Probiotics are the third most commonly consumed dietary supplement after vitamin and mineral preparations. Claimed rationales for probiotics consumption by h ... Read more

Scientist: Dan Tawfik

Organophosphates are toxic compounds found in chemical warfare agents, such as nerve gases, and insect pesticides.Use of volatile nerve gas agents by terrorist organizations is a key concern of governments around the world. V-type nerve agents (e.g. VX, RVX, and CVX) are particularly toxic nerve gases, with an exceptiona ... Read more

Scientist: Yosef Shaul

Triple negative breast cancer (TNBC) is an aggressive type of breast cancer, representing over 10% of all breast cancer cases. TNBC is known for its high risk of relapse, poor survival prospects, and near zero survival rates once TNBC metastasizes. Due to the lack of molecular targets (estrogen, progesterone, and HER2 re ... Read more

Scientist: Zelig Eshhar

Chimeric Antigen Receptor T-Cells (CAR-Ts) are one of the revolutionary technologies of the twenty-first century, invented by Prof. Zelig Eshhar at the Weizmann Institute of Science. The CAR-T technology represents a leap in terms of treating cancer, as the technology programs an individual’s immune system to specifica ... Read more