Pharmaceuticals(41)
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A Novel Platform for Rapid Generation of Covalent Biotherapeutics (No. T4-2282)
Covalent drugs have emerged as a groundbreaking modality for improving the affinity, potency, and duration of action of molecularly targeted inhibitors. Prof. ... Read more18694 -
Adapters for Targeted Viral Vector-Based Therapies (No. T4-2229)
A major challenge in developing viral-based therapies, such as gene therapies, CAR-T cell immunotherapy, and oncolytic virotherapy, is that the most efficient vectors and viruses are not specific, preventing their direct administration to the patient. Prof. ... Read more18691 -
A Novel Treatment for Cancer-Associated Cachexia (No. T4-2221)
Cancer-associated cachexia (CAC) is a late-stage metabolic syndrome characterized by massive weight loss that occurs in 80% of cancer patients and is responsible for 20% of cancer deaths. It does not respond to dietary changes, and there is currently no effective biomarker or treatment for CAC. ... Read more18685 -
An Improved Single-Cell RNA-Sequencing Method (No. T4-2217)
Single-cell RNA sequencing (scRNA-seq) enables the analysis of gene expression in individual cells, unveiling new subsets of cells in different states or diseases through statistical analysis. ... Read more18646 -
Hyperstable Serum Albumin Variants for Microbial Mass Production (No. T4-2216)
Serum albumins are essential in a wide variety of molecular and cellular applications, including in the medical, biotechnological and cultivated meat industries. ... Read more18682 -
High Throughput Screening Platform For Inhibitors of Viral Membrane Fusion (No. T4-2213)
Enveloped viruses pose significant health risks and lack effective treatments. Inhibiting viral membrane fusion, a crucial step in infection, holds promise for antiviral drug development. Dr. ... Read more18679 -
Innovative Immunotherapy for Cardiac Regeneration after Myocardial Infarction (No. T4-2166)
Myocardial infarction (MI), commonly known as a heart attack, is a leading cause of death worldwide, with no available therapies for restoring heart function post-MI. Prof. ... Read more18664 -
Natural Human Antibodies to Treat Cancer (No. T4-2152)
Ovarian cancer is the fifth leading cause of cancer-related death in women. Due to a lack of early detection methods, it is often diagnosed at a late stage, resulting in negligible changes to cure. ... Read more17825 -
Treating myeloid malignancies with Rock inhibitors (No. T4-2147)
Acute myeloid leukemia (AML) incidents increases with age and mortality exceeds 90% when it is diagnosed after the age of 65. Specific mutations were shown to exist in pre-leukemic subjects years before the disease breaks. ... Read more18409 -
Diagnosis and Treatment of Breast Cancer based on Extracellular Vesicles (No. T4-2145)
Early detection of breast cancer (BC) and monitoring its progression, treatment response, and recurrence are crucial for survival. ... Read more16676
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