Ovarian cancer is the fifth leading cause of cancer-related death in women. Due to a lack of early detection methods, it is often diagnosed at a late stage, resulting in negligible changes to cure. ... Read more

Acute myeloid leukemia  (AML) incidents increases with age and mortality exceeds 90% when it is diagnosed after the age of 65. Specific mutations were shown to exist in pre-leukemic subjects years before the disease breaks. ... Read more

Early detection of breast cancer (BC) and monitoring its progression, treatment response, and recurrence are crucial for survival. ... Read more

The constant emergence of new variants threatens the success of the mRNA vaccines developed against SARS-CoV-2. Therefore, there is an urgent need to develop a vaccine that will provide immunity against multiple variants – both existing and potential. Prof. ... Read more

Psychiatric disorders, especially major depressive disorder (MDD), are leading causes of disability and premature death across the globe, with patients showing a heightened risk of self-harm and suicidal ideation. Prof. ... Read more

Of the approximately 30 million adult smokers in the U.S, more than half report attempting to quit smoking every year. However, smoking cessation-associated weight gain (SCWG) constitutes a major obstacle to smoking withdrawal. ... Read more

Ewing sarcoma (ES) is a common bone malignancy in children and young adolescents which is usually treated by systemic chemotherapy. In about 25% of the cases, cancer has already spread to other parts of the body at the time of diagnosis. ... Read more

Proteasomal protein degradation is crucial in maintaining cellular integrity and in regulating key cellular processes including cell cycle, proliferation and cell death. ... Read more

Immunotherapy has revolutionized cancer treatment by activating the immune system to attack tumor cells. However, notable limitations remain, including differential responses between individuals and cancer types. Dr. ... Read more

Alzheimer's Disease (AD) is an age-associated neurodegenerative disorder characterized clinically by a decline in cognitive function. It is the most common type of dementia, with 5.8 million Americans living with AS in 2020. ... Read more